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躯体化综合征患者的心理生理唤醒水平和皮质醇水平升高。

Elevated levels of psychophysiological arousal and cortisol in patients with somatization syndrome.

作者信息

Rief W, Shaw R, Fichter M M

机构信息

Center for Behavioural Medicine, Clinic Roseneck, Prien am Chiemsee, Germany.

出版信息

Psychosom Med. 1998 Mar-Apr;60(2):198-203. doi: 10.1097/00006842-199803000-00016.

DOI:10.1097/00006842-199803000-00016
PMID:9560870
Abstract

OBJECTIVE

This study investigates psychological and psychobiological processes in patients with somatization syndrome.

METHOD

We compared physiological measures (heart rate, finger pulse volume, electrodermal activity, electromyography), cortisol levels, and subjective well-being during rest and during a mental stress task as well as selective attention and memory for illness-related words in 58 patients with somatization syndrome and 21 healthy controls.

RESULTS

The somatization group had higher morning salivary cortisol concentrations, higher heart rates, and lower levels of finger pulse volume. During the mental stress task, patients with somatization syndrome felt more distressed and had higher heart rates, whereas controls showed habituation to the experimental situation. We were unable to demonstrate an attention or memory bias specific for somatization.

CONCLUSIONS

The results point to several psychological, psychophysiological, and psychobiological mechanisms that might be involved in the maintenance of somatization syndrome. These results are discussed from a cognitive-psychobiological perspective.

摘要

目的

本研究调查躯体化综合征患者的心理和心理生物学过程。

方法

我们比较了58例躯体化综合征患者和21名健康对照者在休息和精神应激任务期间的生理指标(心率、手指脉搏容积、皮肤电活动、肌电图)、皮质醇水平和主观幸福感,以及对与疾病相关词汇的选择性注意力和记忆力。

结果

躯体化组早晨唾液皮质醇浓度较高、心率较快、手指脉搏容积较低。在精神应激任务期间,躯体化综合征患者感到更痛苦且心率较高,而对照组对实验情境表现出适应性。我们未能证明对躯体化有特定的注意力或记忆偏差。

结论

结果指出了可能参与躯体化综合征维持的几种心理、心理生理和心理生物学机制。从认知心理生物学角度对这些结果进行了讨论。

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