Bilir E, Craven W, Hugg J, Gilliam F, Martin R, Faught E, Kuzniecky R
UAB Epilepsy Center, Department of Neurology, University of Alabama at Birmingham 35294, USA.
Neuroradiology. 1998 Mar;40(3):138-44. doi: 10.1007/s002340050554.
The limbic system comprises the hippocampal formation, fornix, mamillary bodies, thalamus, and other integrated structures. It is involved in complex functions including memory and emotion and in diseases such as temporal lobe epilepsy. Volume measurements of the amygdala and hippocampus have been used reliably to study patients with temporal lobe epilepsy but have not extended to other limbic structures. We performed volume measurements of hippocampus, amygdala, fornix and mamillary bodies in healthy individuals. Measurements of the amygdala, hippocampus, fornix and mamillary bodies revealed significant differences in volume between right and left sides (P < 0.001). The intraclass coefficient of variation for measurements was high for all structures except the mamillary bodies. Qualitative image assessment of the same structures revealed no asymmetries between the hemispheres. This technique can be applied to the study of disorders affecting the limbic system.
边缘系统由海马结构、穹窿、乳头体、丘脑及其他整合结构组成。它参与包括记忆和情感在内的复杂功能，以及颞叶癫痫等疾病。杏仁核和海马体的体积测量已被可靠地用于研究颞叶癫痫患者，但尚未扩展到其他边缘结构。我们对健康个体的海马体、杏仁核、穹窿和乳头体进行了体积测量。杏仁核、海马体、穹窿和乳头体的测量显示左右两侧体积存在显著差异（P < 0.001）。除乳头体外，所有结构测量的组内变异系数都很高。对相同结构的定性图像评估显示半球之间没有不对称性。该技术可应用于影响边缘系统疾病的研究。
