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胆胰转流术治疗病态肥胖症:50例经验

Biliopancreatic diversion for treatment of morbid obesity: experience in 50 cases.

作者信息

Noya G, Cossu M L, Coppola M, Tonolo G, Angius M F, Fais E, Ruggiu M

机构信息

Cattedra di Chirurgia d'Urgenza e Clinica Chirurgica generale, Universita' di Sassari, Italy.

出版信息

Obes Surg. 1998 Feb;8(1):61-6. doi: 10.1381/096089298765555079.

Abstract

BACKGROUND

Biliopancreatic diversion (BPD) by Scopinaro's method is an operation advocated by some surgeons as an effective treatment for morbid obesity.

METHODS

Between February 1995 and April 1997 we performed BPD by Scopinaro's method on 50 patients with morbid obesity (23 males), average age 41.4 years (range 20-63 years), average body weight 135.08 kg (range 89-256 kg), mean body mass index (BMI) 50.65 kg/m2 (range 37.01-81.56 kg/m2).

RESULTS

In all cases a gradual decrease in weight was obtained [mean BMI at 1 month: 44.8 kg/m2, at 6 months (31 patients): 35.09 kg/m2, at 1 year (23 patients): 31.36 kg/m2, at 18 months (14 patients): 29.89 kg/m2 and at 2 years (5 patients): 29.27 kg/m2]. At the same time a significant improvement in the pathological conditions associated with morbid obesity was observed. The patients were able to suspend oral antihypertensive and antidiabetic therapy as these parameters spontaneously returned to normal values by the sixth postoperative month; all cases showed a marked reduction in hypercholesterolemia and hypertriglyceridemia. Postoperative complications were: one death (2%) on the third day due to heart failure; two late intestinal occlusions (4%); one acute dilatation of the stomach (2%); one peritonitis caused by early dehiscence of the anastomosis (2%); five anastomotic ulcers (10%); two cases of protein malnutrition (4%).

CONCLUSIONS

BPD by Scopinaro's method is a bariatric procedure which is technically complex. However is it safe and reproducible and it induces a substantial weight loss.

摘要

背景

斯科皮纳罗法胆胰转流术(BPD)是一些外科医生所倡导的一种治疗病态肥胖的有效手术方法。

方法

1995年2月至1997年4月期间,我们采用斯科皮纳罗法对50例病态肥胖患者(23例男性)实施了BPD手术,患者平均年龄41.4岁(范围20 - 63岁),平均体重135.08千克(范围89 - 256千克),平均体重指数(BMI)为50.65千克/平方米(范围37.01 - 81.56千克/平方米)。

结果

所有病例体重均逐渐下降[术后1个月时平均BMI为44.8千克/平方米,6个月时(31例患者)为35.09千克/平方米,1年时(23例患者)为31.36千克/平方米,18个月时(14例患者)为29.89千克/平方米,2年时(5例患者)为29.27千克/平方米]。同时,观察到与病态肥胖相关的病理状况有显著改善。患者能够停用口服抗高血压和抗糖尿病药物,因为这些指标在术后第六个月时自发恢复到正常水平;所有病例的高胆固醇血症和高甘油三酯血症均有明显降低。术后并发症包括:术后第三天因心力衰竭死亡1例(2%);晚期肠梗阻2例(4%);急性胃扩张1例(2%);吻合口早期裂开导致腹膜炎1例(2%);吻合口溃疡5例(10%);蛋白质营养不良2例(4%)。

结论

斯科皮纳罗法BPD是一种技术复杂的减肥手术。然而,它是安全且可重复的,能导致显著的体重减轻。

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