Wylezol M, Gluck M, Zubik R, Kobielski A, Pardela M
Department of General and Bariatric Surgery, Zabrze, Medical University of Silesia, Katowice, Poland.
J Physiol Pharmacol. 2005 Dec;56 Suppl 6:117-26.
Biliopancreatic diversion (BPD) is a bariatric operation of proved efficacy especially in patients with metabolic comorbidities. The aim was to assess the results of BPD in relation to weight loss and coexisting lipid and glucose metabolism disturbances in the Polish population. Between October 2001 and December 2003 57 morbidly obese patients (24 male and 33 female) underwent BPD. Median age was 46 years (range: 17-58) and median body mass index (BMI) was 50.2 kg/m(2) (range: 40.1-73 kg/m(2)). Type 2 diabetes mellitus was observed in 11 patients (19.3%), hypercholesterolaemia in 38 patients (66.7%) and hypertriglyceridaemia in 37 patients (64.9%). Median value of BMI decreased at three months to 40.0 kg/m(2), at six months to 36.7 kg/m(2), and after a year to 32.3 kg/m2. Diabetes was completely resolved in all patients. After six months, triglycerides and cholesterol levels were higher than normal only in one patient. Early specific complications that manifested as seroma and nosocomial pneumonia occurred in 5.3% and 3.5% patients, respectively. The following specific late complications were observed: ulceration of stomach stump (3.4%), anaemia (14.0%), hypoalbuminaemia (8.8%), deterioration of haemorrhoids (15.8). All of above complications were treated conservatively expect two haemorrhoidectomies. One patient died due to myocardial infarction eight months after BPD. Five cases of incisional hernias (8.8%) were found. BPD is an effective bariatric procedure also in the Polish population, resulting not only in weight loss but also in the improvement of lipid and glucose metabolism.
胆胰转流术（BPD）是一种已证实疗效显著的减肥手术，尤其适用于患有代谢性合并症的患者。目的是评估波兰人群中BPD手术在体重减轻以及并存的脂质和葡萄糖代谢紊乱方面的效果。2001年10月至2003年12月期间，57例病态肥胖患者（24例男性和33例女性）接受了BPD手术。中位年龄为46岁（范围：17 - 58岁），中位体重指数（BMI）为50.2 kg/m²（范围：40.1 - 73 kg/m²）。11例患者（19.3%）患有2型糖尿病，38例患者（66.7%）患有高胆固醇血症，37例患者（64.9%）患有高甘油三酯血症。BMI的中位值在术后三个月降至40.0 kg/m²，六个月降至36.7 kg/m²，一年后降至32.3 kg/m²。所有患者的糖尿病均完全缓解。六个月后，仅1例患者的甘油三酯和胆固醇水平高于正常。早期特定并发症表现为血清肿和医院获得性肺炎，分别发生在5.3%和3.5%的患者中。观察到以下特定的晚期并发症：胃残端溃疡（3.4%）、贫血（14.0%）、低白蛋白血症（8.8%）、痔疮恶化（15.8%）。除了两例痔疮切除术外，上述所有并发症均采用保守治疗。1例患者在BPD手术后八个月因心肌梗死死亡。发现5例切口疝（8.8%）。BPD手术在波兰人群中也是一种有效的减肥手术，不仅能减轻体重，还能改善脂质和葡萄糖代谢。
