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胆胰转流术治疗病态肥胖症:180例连续病例的经验。

Biliopancreatic diversion for treatment of morbid obesity: experience in 180 consecutive cases.

作者信息

Totté E, Hendrickx L, van Hee R

机构信息

Academic Surgical Center Stuivenberg, Antwerp, Belgium.

出版信息

Obes Surg. 1999 Apr;9(2):161-5. doi: 10.1381/096089299765553412.

Abstract

BACKGROUND

Biliopancreatic diversion (BPD) by Scopinaro's method is used by many as a surgical treatment for morbid obesity. The authors present their results in 180 consecutive cases.

METHOD

Between June 1995 and May 1998, the authors performed BPD by Scopinaro's method on 180 patients (36 men) with morbid obesity, mean age 35.8 years (range 18-58 years), mean body mass index (BMI) 48.8 kg/m2 (range 35-66 kg/m2).

RESULTS

In all cases, a gradual decrease in weight was obtained: the mean BMI at 1 month was 40.3 kg/m2, at 6 months 34 kg/m2, at 1 years 32 kg/m2, at 18 months 30.2 kg/m2, and at 36 months 28.8 kg/m2. At the same time a significant improvement in the pathologic conditions associated with morbid obesity was observed. Postoperative complications were two duodenum blowout syndromes requiring prolonged intensive care, and an 18% rate of incisional hernias. Conversion to normal small bowel continuity was necessary in three cases. Protein malnutrition developed in 2 patients (1.1%), in 1 patient coinciding with addiction to cocaine. One patient could not psychologically accept the physical changes and requested conversion. Anastomotic ulceration was seen in 11% of the patients. Operation for late obstruction occurred in 2 patients. There was no mortality.

CONCLUSIONS

Although BPD by Scopinaro's method is technically complex, it is safe and effective.

摘要

背景

许多人采用斯科皮纳罗方法进行的胆胰转流术(BPD)来治疗病态肥胖症。作者介绍了他们连续180例病例的治疗结果。

方法

1995年6月至1998年5月期间,作者采用斯科皮纳罗方法对180例病态肥胖患者(36例男性)实施了BPD,患者平均年龄35.8岁(范围18 - 58岁),平均体重指数(BMI)为48.8kg/m²(范围35 - 66kg/m²)。

结果

所有病例体重均逐渐下降:1个月时平均BMI为40.3kg/m²,6个月时为34kg/m²,1年时为32kg/m²,18个月时为30.2kg/m²,36个月时为28.8kg/m²。同时,观察到与病态肥胖相关的病理状况有显著改善。术后并发症包括2例十二指肠破裂综合征,需要长时间重症监护,切口疝发生率为18%。3例患者需要恢复正常小肠连续性。2例患者(1.1%)出现蛋白质营养不良,其中1例与可卡因成瘾同时发生。1例患者在心理上无法接受身体变化,要求恢复原状。11%的患者出现吻合口溃疡。2例患者发生晚期梗阻手术。无死亡病例。

结论

尽管斯科皮纳罗方法的BPD技术复杂,但安全有效。

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