Golding J S, Blackburne J S
J Bone Joint Surg Br. 1976 Aug;58(3):350-2. doi: 10.1302/0301-620X.58B3.956255.
Twenty-six index patients with primary Madelung's deformity of the wrist were examined, as were sixty-five of their relatives. Standard radiographs were taken and measured to determine whether mesomelic dwarfism, a feature of dyschondrosteosis, was present. No case of mesomelia was found. No evidence of Madelung's deformity was found in the relatives of the index patients, who were all female. It is concluded that primary Madelung's deformity of the wrist is not an expressions of dyschondrosteosis, that it is not inherited, and that it does not occur in the male. One index patient with dyschondrosteosis was examined. Eight of her relatives were similarly affected, and three of these were male. It is suggested that previously recorded male cases of Madelung's deformity of the wrist were expressions of dyschondrosteosis or of secondary deformity.
对26例原发性腕关节马德隆畸形患者及其65名亲属进行了检查。拍摄标准X线片并进行测量，以确定是否存在作为软骨发育不全特征的中肢侏儒症。未发现中肢短小的病例。在所有为女性的先证者亲属中未发现马德隆畸形的证据。结论是，原发性腕关节马德隆畸形不是软骨发育不全的表现，不具有遗传性，且男性不会发生。对1例软骨发育不全的先证者进行了检查。她的8名亲属也有类似症状，其中3名是男性。有人提出，先前记录的男性腕关节马德隆畸形病例是软骨发育不全或继发性畸形的表现。
