Chaloupka J C, Huddle D C
Department of Radiology, Yale University School of Medicine, New Haven, Connecticut 06510, USA.
Neuroimaging Clin N Am. 1998 May;8(2):295-321.
The ability to systematically and meaningfully classify a disease is in many ways a reflection of our overall understanding of it. Over time, nosologic schemes applied to any disease typically undergo a characteristic evolution from purely descriptive, to pathoanatomic and/or embryologic, to finally biological definitions. With the recent developments in further elucidating the pathophysiology, histopathology, natural history, and cellular biology of various vascular malformations occurring within the central nervous system, it is time to derive a more comprehensive and "universal" classification system that integrates classic pathoanatomic schemes with a biologically defined scheme previously developed for systematic vascular malformations. Such a system is proposed and discussed, including detailed review of important subtypes.
能够系统且有意义地对一种疾病进行分类，在很多方面反映了我们对它的整体理解。随着时间推移，应用于任何疾病的疾病分类方案通常会经历一个典型的演变过程，从纯粹的描述性，到病理解剖学和/或胚胎学，最终到生物学定义。随着最近在进一步阐明中枢神经系统内各种血管畸形的病理生理学、组织病理学、自然史和细胞生物学方面取得的进展，现在是时候推导一个更全面且“通用”的分类系统了，该系统将经典的病理解剖学方案与先前为系统性血管畸形开发的生物学定义方案相结合。本文提出并讨论了这样一个系统，包括对重要亚型的详细回顾。
