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儿童伤口感染:一项前瞻性多中心研究。

Pediatric wound infections: a prospective multicenter study.

作者信息

Horwitz J R, Chwals W J, Doski J J, Suescun E A, Cheu H W, Lally K P

机构信息

University of Texas-Houston Medical School and Hermann Children's Hospital, USA.

出版信息

Ann Surg. 1998 Apr;227(4):553-8. doi: 10.1097/00000658-199804000-00017.

Abstract

OBJECTIVE

Surgical wound infections remain a significant source of postoperative morbidity. This study was undertaken to determine prospectively the incidence of postoperative wound infections in children in a multi-institutional fashion and to identify the risk factors associated with the development of a wound infection in this population.

SUMMARY BACKGROUND DATA

Despite a large body of literature in adults, there have been only two reports from North America concerning postoperative wound infections in children.

METHODS

All infants and children undergoing operation on the pediatric surgical services of three institutions during a 17-month period were prospectively followed for 30 days after surgery for the development of a wound infection.

RESULTS

A total of 846 of 1021 patients were followed for 30 days. The overall incidence of wound infection was 4.4%. Factors found to be significantly associated with a postoperative wound infection were the amount of contamination at operation (p = 0.006) and the duration of the operation (p = 0.03). Comparing children who developed a wound infection with those who did not, there were no significant differences in age, sex, American Society of Anesthesiologists (ASA) preoperative assessment score, length of preoperative hospitalization, location of operation (intensive care unit vs. operating room), presence of a coexisting disease or remote infection, or the use of perioperative antibiotics.

CONCLUSIONS

Our results suggest that wound infections in children are related more to the factors at operation than to the overall physiologic status. Procedures can be performed in the intensive care unit without any increase in the incidence of wound infection.

摘要

目的

手术伤口感染仍是术后发病的重要来源。本研究旨在以前瞻性、多机构的方式确定儿童术后伤口感染的发生率,并确定该人群中与伤口感染发生相关的危险因素。

总结背景数据

尽管有大量关于成人术后伤口感染的文献,但北美仅有两篇关于儿童术后伤口感染的报道。

方法

在17个月的时间里,对三家机构小儿外科接受手术的所有婴幼儿和儿童进行术后30天的前瞻性随访,观察伤口感染的发生情况。

结果

1021例患者中共有846例接受了30天的随访。伤口感染的总体发生率为4.4%。发现与术后伤口感染显著相关的因素是手术时的污染程度(p = 0.006)和手术持续时间(p = 0.03)。将发生伤口感染的儿童与未发生感染的儿童进行比较,在年龄、性别、美国麻醉医师协会(ASA)术前评估评分、术前住院时间、手术地点(重症监护病房与手术室)、是否存在并存疾病或远处感染,或围手术期抗生素的使用方面,均无显著差异。

结论

我们的结果表明,儿童伤口感染更多地与手术因素有关,而非整体生理状态。在重症监护病房进行手术不会增加伤口感染的发生率。

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