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[腰椎松质骨和皮质骨的骨密度。与欧洲椎体骨质疏松症研究(EVOS)一个地区人群的性别、年龄和脊柱畸形的关系]

[Bone density of spongiosa and cortical bone of the lumbar spine. Relations to sex, age and spinal deformities in a regional collective of the European Study of Vertebral Osteoporosis (EVOS)].

作者信息

Banzer D, Fabian C, Andresen R, Banzer J P, Felsenberg D, Reisinger W, Neher K M

机构信息

Städtisches Krankenhaus Zehlendorf (Behringkrankenhaus), Akademisches Lehrkrankenhaus, Freien Universität Berlin.

出版信息

Med Klin (Munich). 1998 Mar 15;93 Suppl 2:56-62,64-5. doi: 10.1007/BF03042000.

DOI:10.1007/BF03042000
PMID:9564159
Abstract

BACKGROUND AND METHOD

In an additional bone density measurement protocol to the European Vertebral Osteoporosis Study (EVOS) separate spongious and cortical density measurements (sQCT) were carried out at the first 3 lumbar vertebrae in 293 volunteers (92 men and 201 women) in 3 Berlin regional centers.

RESULTS

The spongious mineral density decreases from proximal to distal (L1 to L3), the cortical density increases from proximal to distal, mainly in men. Men showed no significant decrease of cortical density and a lower decrease of spongious density with age compared to women. A comparison of bone mineral density with vertebral height indices of McCloskey/Kanis, Eastell/Melton and Felsenberg showed significant differences of spongious density between a group with normal vertebral height and a group with at least one pathologically degraded vertebra. Individuals with osteoporosis according to the WHO-definition showed a higher prevalence of vertebral deformities. No significant loss of cortical density was observed in these people.

摘要

背景与方法

在一项针对欧洲椎体骨质疏松研究(EVOS)的额外骨密度测量方案中,在柏林的3个区域中心对293名志愿者(92名男性和201名女性)的第1至第3腰椎进行了松质骨和皮质骨密度的单独测量(扇形束CT)。

结果

松质骨矿物质密度从近端(L1)到远端(L3)降低,皮质骨密度从近端到远端增加,主要见于男性。与女性相比,男性皮质骨密度没有显著降低,且随着年龄增长松质骨密度降低幅度较小。将骨矿物质密度与McCloskey/Kanis、Eastell/Melton和Felsenberg的椎体高度指数进行比较,结果显示椎体高度正常组与至少有一个椎体病理性退变组之间的松质骨密度存在显著差异。根据世界卫生组织定义患有骨质疏松症的个体椎体畸形患病率更高。在这些人中未观察到皮质骨密度有显著降低。

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