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[儿童阻塞性睡眠呼吸暂停:一种特别关注颅面变化的多学科治疗理念]

[Obstructive sleep apnea in the child: an interdisciplinary treatment concept with special reference to craniofacial changes].

作者信息

Hochban W, Hoch B

机构信息

Klinik für Mund-, Kiefer-, Gesichtschirurgie, Philipps-Universität Marburg.

出版信息

Pneumologie. 1998 Mar;52(3):147-53.

PMID:9564188
Abstract

Diagnosis and therapy of obstructive sleep-related breathing disturbances SRBD in adults may not be applied without hesitation to children. SRBD in newborn and infants are often due to craniofacial disturbances (Pierre Robin syndrome, Goldenhars syndrome etc.), obesity is of minor importance. More than 30 infants with SRBD and craniofacial changes have been diagnosed and successfully treated over a 2-year period. Conservative therapy starts immediately after birth. The first step in newborn with Pierre Robin syndrome, for instance, is prone position for protrusion of tongue and mandible and mandibular growth stimulation. Intermediate nightly nasopharyngeal tubes are an alternative to nCPAP-/BiPAP treatment. Conventional orthopaedic/orthodontic treatment should not be neglected, even if it takes years to become effective. Surgical therapies are able to support, sometimes to replace or at least to shorten conservative methods. In rare cases when prone position in combination with palatal plates in cases of Robin syndrome, for instance, are not fully effective, mandibular extension is indicated. Aplasia or defects demand adequate surgical reconstruction, even if this does not necessarily mean abolishment of SRBD. In contrast to adults adenotonsillectomy is highly effective in infants and does not only reduce SRBD, but also improves nasal breathing and thus positively influences facial growth. A relatively new method is gradual mandibular distraction osteogenesis according to Ilizarov, which also enhances soft tissue growth. Maxillary and mandibular advancement osteotomies should not be considered before the termination of facial growth. Thanks to this refined treatment concept we were able to avoid tracheotomies in children during the past few years.

摘要

成人阻塞性睡眠相关呼吸障碍(SRBD)的诊断和治疗方法不能毫不犹豫地应用于儿童。新生儿和婴儿的SRBD通常是由颅面紊乱(如皮埃尔·罗宾综合征、戈尔登哈综合征等)引起的,肥胖的影响较小。在两年时间里,已诊断并成功治疗了30多名患有SRBD和颅面改变的婴儿。保守治疗在出生后立即开始。例如,患有皮埃尔·罗宾综合征的新生儿的第一步是采取俯卧位,以促进舌头和下颌突出以及刺激下颌生长。夜间使用中间型鼻咽管是持续气道正压通气/双水平气道正压通气治疗的一种替代方法。即使传统的骨科/正畸治疗需要数年才能起效,也不应忽视。手术治疗能够起到辅助作用,有时可以替代或至少缩短保守治疗方法。例如,在罕见情况下,当罗宾综合征患者采取俯卧位并结合腭板治疗效果不完全理想时,需要进行下颌延长术。发育不全或缺陷需要进行适当的手术重建,即使这不一定意味着消除SRBD。与成人不同,腺样体扁桃体切除术在婴儿中非常有效,不仅可以减少SRBD,还能改善鼻腔通气,从而对面部生长产生积极影响。一种相对较新的方法是根据伊里扎洛夫技术进行渐进性下颌骨牵张成骨术,这也能促进软组织生长。在上颌骨和下颌骨生长结束之前,不应考虑进行上颌骨和下颌骨前徙截骨术。由于这种精细的治疗理念,在过去几年里我们得以避免对儿童进行气管切开术。

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[Obstructive sleep apnea in the child: an interdisciplinary treatment concept with special reference to craniofacial changes].[儿童阻塞性睡眠呼吸暂停:一种特别关注颅面变化的多学科治疗理念]
Pneumologie. 1998 Mar;52(3):147-53.
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Mandibular traction--an alternative treatment in infants with Pierre Robin sequence.下颌骨牵引——皮埃尔·罗宾序列征婴儿的一种替代治疗方法。
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Mandibular distraction osteogenesis for Pierre Robin sequence: what percentage of neonates need it?下颌骨牵张成骨术治疗Pierre Robin序列征:新生儿中需要该治疗的比例是多少?
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[Surgical treatment of obstructive sleep apnea by osteotomy of the facial bones (results of 1 year)].[面部骨骼截骨术治疗阻塞性睡眠呼吸暂停(1年结果)]
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Bilateral intra-oral distraction osteogenesis for the management of severe congenital mandibular hypoplasia in early childhood.双侧口腔内牵张成骨术治疗儿童早期严重先天性下颌骨发育不全
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