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分泌型免疫球蛋白A与心算及冷加压试验的心血管反应

Secretory immunoglobulin A and cardiovascular reactions to mental arithmetic and cold pressor.

作者信息

Willemsen G, Ring C, Carroll D, Evans P, Clow A, Hucklebridge F

机构信息

School of Sport and Exercise Sciences, University of Birmingham, UK.

出版信息

Psychophysiology. 1998 May;35(3):252-9.

PMID:9564745
Abstract

Secretory immunoglobulin A (sIgA) in saliva and cardiovascular reactions to mental arithmetic and cold pressor tasks were recorded in 16 healthy young men on two sessions, 4 weeks apart. Both tasks elicited significant increases in sIgA secretion rate, reflecting increases in both salivary volume and sIgA concentration. Whereas mental arithmetic elicited a mixed pattern of alpha- and beta-adrenergic cardiovascular reactions, the pattern of reactions to cold pressor was predominantly alpha-adrenergic. Task levels of sIgA secretion rate, sIgA concentration, and saliva volume showed moderate to high test-retest reliability (r = .52-.83), although test-retest correlations were less impressive for change scores (r = -.19-.53). The pattern of correlations between change in sIgA secretion rate and cardiovascular reactivity variables was inconsistent.

摘要

对16名健康年轻男性进行了两个阶段的记录,两阶段相隔4周,记录了他们唾液中的分泌型免疫球蛋白A(sIgA)以及对心算和冷加压任务的心血管反应。两项任务均引起sIgA分泌率显著增加,这反映了唾液量和sIgA浓度的增加。心算引起了α-和β-肾上腺素能心血管反应的混合模式,而冷加压反应模式主要是α-肾上腺素能。sIgA分泌率、sIgA浓度和唾液量的任务水平显示出中度至高的重测信度(r = 0.52 - 0.83),尽管变化分数的重测相关性不那么显著(r = -0.19 - 0.53)。sIgA分泌率变化与心血管反应性变量之间的相关模式并不一致。

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