Santamaría J, García A M, de Vicente J C, Landa S, López-Arranz J S
Department of Maxillofacial Surgery, Hospital of Cruces, Bilbao, Basque country, Spain.
Int J Oral Maxillofac Surg. 1998 Apr;27(2):118-20. doi: 10.1016/s0901-5027(98)80308-1.
In order to determine the degree of bone regeneration after removal of radicular cysts using guided bone regeneration (GBR), a prospective, controlled and randomized clinical study was performed. Thirty patients with radicular cysts were divided into three groups. One group, the control group (n=10 patients), was treated by enucleation and primary closure. The other two groups were treated by enucleation and primary closure but GBR was used in addition, using a resorbable membrane (n=10) and a nonresorbable membrane (n=10). The membranes were fixed with nonresorbable Memfix System screws. The residual volume and the density of the newly formed tissue was measured by computer-assisted tomography and computer-assisted digital image analysis before enucleation and three and six months postoperatively. No statistical significance was found in density and residual volume between the three treatment groups after six months. These results suggest that GBR using membranes does not contribute to increased bone regeneration.
为了确定使用引导骨再生（GBR）技术摘除牙根囊肿后骨再生的程度，进行了一项前瞻性、对照和随机的临床研究。30例牙根囊肿患者被分为三组。一组为对照组（n = 10例患者），采用摘除术和一期缝合治疗。另外两组也采用摘除术和一期缝合，但额外使用了GBR技术，分别使用可吸收膜（n = 10）和不可吸收膜（n = 10）。这些膜用不可吸收的Memfix系统螺钉固定。在摘除术前以及术后3个月和6个月，通过计算机断层扫描和计算机辅助数字图像分析测量新形成组织的残余体积和密度。6个月后，三个治疗组之间在密度和残余体积方面未发现统计学差异。这些结果表明，使用膜的GBR技术对增加骨再生没有作用。
