Scholer S J, Hickson G B, Mitchel E F, Ray W A
Department of Pediatrics, Division of General Pediatrics, Vanderbilt University, Nashville, TN 37232-8555, USA.
Pediatrics. 1998 May;101(5):E12. doi: 10.1542/peds.101.5.e12.
In the United States in 1994, fires claimed 3.75 lives per 100 000 child years and accounted for 17.3% of all injury deaths in children <5 years of age.
To conduct a historical cohort study that uses maternal demographic characteristics to identify young children at high risk of fire-related deaths, thus defining appropriate targets for prevention programs.
The cohort consisted of children born to mothers who resided in the state of Tennessee between 1980 and 1995. Information was obtained by linking birth certificates, 1990 census data, and death certificates. Children were eligible for the study if they were <5 years of age at any time within the study period and if key study variables were present (99.2% of births). Birth certificates provided information on maternal characteristics including age, race, education, previous live births, use of prenatal care, and residence (in standard metropolitan statistical area). Child characteristics included gender, gestational age, and birth type (singleton/multiple gestation). Neighborhood income was estimated by linking the mother's address at the time of birth to the 1990 census (block group mean per capita income). The study outcome was a fire resulting in at least one fatality (fatal fire event) during the study period, identified from death certificates (coded E880 through E889 in the International Classification of Diseases, 9th rev). We calculated the fatal fire event rate corresponding to each stratum of maternal/child characteristics. We assessed the independent association between each characteristic and the risk of a fatal fire event from a Poisson regression multivariate analysis.
During the study period, 1 428 694 children contributed 5 415 213 child years to the cohort: there were 270 deaths from fire (4.99 deaths per 100 000 child years) and 231 fatal fire events. In the multivariate analysis, factors associated with greater than a threefold increase in fatal fire events included maternal education, age, and number of other children. Compared with children whose mothers had a college education, children whose mothers had less than a high school education had 19.4 times (95% confidence interval [CI], 2.6-142.4) an increased risk of a fatal fire event. Children whose mothers had more than two other children had 6.1 times (95% CI, 3.8-9.8) an increased risk of a fatal fire event compared with children whose mothers had no other children. Children of mothers <20 years of age had 3.9 times (95% CI, 2.2-7.1) increased risk of a fatal fire event compared with children whose mothers were >/=30 years old. Although both maternal neighborhood income and race were associated strongly with increased rates of fatal fire events in the univariate analysis, this association did not persist in the multivariate analysis. Other factors that were associated with increased risk of fatal fire events in the multivariate analysis were male gender and having a mother who was unmarried or who had delayed prenatal care. The three factors associated most strongly with fire mortality were combined to create a risk score based on maternal education (>/=16 years, 0 points; 13 to 15 years, 1 point; 12 years, 2 points; <12 years, 3 points); age (>/=30 years, 0 points; 25 to 29 years, 1 point; 20 to 24 years, 2 points; <20 years, 3 points); and number of other children (none, 0 points; one, 1 point; two, 2 points; three or more, 3 points). The lowest-risk group (score <3) included 19% of the population and had 0.19 fatal fire events per 100 000 child years. In contrast, highest-risk children (score >7) comprised 1.5% of the population and had 28.6 fatal fire events per 100 000 child years, 150 times higher than low-risk children. Children with risk scores >5 contributed 26% of child years but experienced 68% of all fatal fire events. If the fatal fire event rate for all children had been equal to that of the low-risk group (risk score <3), then 95% of deaths from
1994年在美国,每10万个儿童年中有3.75人死于火灾,占5岁以下儿童所有伤害死亡人数的17.3%。
开展一项历史性队列研究,利用母亲的人口统计学特征来识别与火灾相关死亡风险高的幼儿,从而为预防项目确定合适的目标人群。
队列由1980年至1995年期间居住在田纳西州的母亲所生的儿童组成。通过链接出生证明、1990年人口普查数据和死亡证明来获取信息。如果儿童在研究期间的任何时候年龄小于5岁且存在关键研究变量(99.2%的出生情况),则符合研究条件。出生证明提供了关于母亲特征的信息,包括年龄、种族、教育程度、既往活产情况、产前护理的使用情况以及居住地(标准大都市统计区)。儿童特征包括性别、孕周和出生类型(单胎/多胎妊娠)。通过将母亲出生时的住址与1990年人口普查数据相链接来估计邻里收入(街区组人均收入)。研究结局是在研究期间发生的导致至少一人死亡的火灾(致命火灾事件),从死亡证明中识别(国际疾病分类第9版编码为E880至E889)。我们计算了对应于每个母亲/儿童特征分层的致命火灾事件发生率。我们通过泊松回归多变量分析评估了每个特征与致命火灾事件风险之间的独立关联。
在研究期间,1428694名儿童为队列贡献了5415213个儿童年:有270例火灾死亡(每10万个儿童年中有4.99人死亡)和231起致命火灾事件。在多变量分析中,与致命火灾事件增加三倍以上相关的因素包括母亲的教育程度、年龄和其他子女数量。与母亲拥有大学学历的儿童相比,母亲学历低于高中的儿童发生致命火灾事件的风险增加了19.4倍(95%置信区间[CI],2.6 - 142.4)。与母亲没有其他子女的儿童相比,母亲有两个以上其他子女的儿童发生致命火灾事件的风险增加了6.1倍(95% CI,3.8 - 9.8)。与母亲年龄≥30岁的儿童相比,母亲年龄<20岁的儿童发生致命火灾事件的风险增加了3.9倍(95% CI,2.2 - 7.1)。尽管在单变量分析中母亲的邻里收入和种族都与致命火灾事件发生率的增加密切相关,但在多变量分析中这种关联并未持续存在。在多变量分析中与致命火灾事件风险增加相关的其他因素包括男性性别以及母亲未婚或延迟进行产前护理。将与火灾死亡率关联最密切的三个因素结合起来,根据母亲的教育程度(≥16岁,0分;13至15岁,1分;12岁,2分;<12岁,3分)、年龄(≥30岁,0分;25至29岁,1分;20至24岁,2分;<20岁,3分)和其他子女数量(无,0分;一个,1分;两个,2分;三个或更多,3分)创建了一个风险评分。风险最低的组(评分<3)包括19%的人群,每10万个儿童年中有0.19起致命火灾事件。相比之下,风险最高的儿童(评分>7)占人群的1.5%,每10万个儿童年中有28.6起致命火灾事件,是低风险儿童的150倍。风险评分>5的儿童贡献了26%的儿童年,但经历了所有致命火灾事件的68%。如果所有儿童的致命火灾事件发生率与低风险组(风险评分<3)相同,那么95%的死亡将来自……