Andrykowski M A, Cordova M J
University of Kentucky College of Medicine, Lexington 40536-0086, USA.
J Trauma Stress. 1998 Apr;11(2):189-203. doi: 10.1023/A:1024490718043.
The utility of Andersen's (1993, 1994) model of psychologic morbidity following cancer treatment for predicting PTSD symptoms in breast cancer survivors (N = 82) was examined. PTSD symptoms, physical comorbidity, social support, depression history, and pre-cancer traumatic stressors were assessed in a structured telephone interview. Multiple regression analysis indicated that Andersen model variables (physical comorbidity, education, disease stage, cancer treatment, depression history, social support) accounted for 39% of variance in PTSD symptom reports (p < .001). Addition to the model of time since treatment completion, pre-cancer traumatic stressors, age at diagnosis, and tamoxifen usage accounted for an additional 16% of variance (p < .001). Higher levels of PTSD symptoms were associated with less social support, greater pre-cancer trauma history, less time since treatment completion, and more advanced disease.
本研究检验了安德森(1993年、1994年)提出的癌症治疗后心理疾病模型对预测乳腺癌幸存者(N = 82)创伤后应激障碍(PTSD)症状的效用。通过结构化电话访谈评估了PTSD症状、身体共病情况、社会支持、抑郁病史以及癌症前创伤应激源。多元回归分析表明,安德森模型变量(身体共病情况、教育程度、疾病阶段、癌症治疗、抑郁病史、社会支持)解释了PTSD症状报告中39%的方差变异(p <.001)。在模型中加入治疗结束后的时间、癌症前创伤应激源、诊断时年龄以及他莫昔芬使用情况后,又解释了另外16%的方差变异(p <.001)。较高水平的PTSD症状与较少的社会支持、更严重的癌症前创伤史、较短的治疗结束后时间以及更晚期的疾病相关。