Stebbings S, Highton J, Croxson M C, Powell K, McKay J, Rietveld J
Department of Medicine, Dunedin School of Medicine, Auckland Hospital, New Zealand.
Br J Rheumatol. 1998 Mar;37(3):311-3. doi: 10.1093/rheumatology/37.3.311.
A case of chickenpox monoarthritis is described. The presence of varicella zoster virus (VZV) within the joint was demonstrated by the detection of viral DNA in synovial fluid at a time when peripheral blood cells were negative. This strongly suggests a direct role of VZV in causing monoarthritis complicating chickenpox. The use of the polymerase chain reaction allows more rapid (2 days) confirmation of the diagnosis. Early enough diagnosis would raise the question of using acyclovir to shorten the duration of arthritis.
本文描述了一例水痘性单关节炎病例。在外周血细胞呈阴性时，通过检测滑液中的病毒DNA证实关节内存在水痘带状疱疹病毒（VZV）。这有力地表明VZV在导致水痘并发单关节炎中起直接作用。聚合酶链反应的应用可使诊断更快得到确认（2天）。尽早诊断会引发关于使用阿昔洛韦来缩短关节炎病程的问题。
