Matsuyama W, Mizoguchi A, Iwami F, Hirotsu Y, Kawabata M, Osame M
Department of Respiratory Medicine, Minami Kyushu National Hospital.
Nihon Kyobu Shikkan Gakkai Zasshi. 1997 Dec;35(12):1407-12.
Patient 1: An 18-year-old woman was admitted to our hospital with pneumothorax. She had no history of smoking. Chest CT showed multiple cysts, and pulmonary eosinophilic granuloma was diagnosed by open lung biopsy. She recovered without therapy 3 months later and a chest CT taken at that time was normal. She began smoking, 3 years later, and bore two children. She is without recurrence after 8 years. Patient 2: A 23-year-old man was admitted to our hospital with pneumothorax. He had a smoking history (index = 180). Chest CT showed multiple cysts, and pulmonary eosinophilic granuloma was diagnosed by open lung biopsy. He stopped smoking and recovered without therapy one month later, and subsequently, his CT findings returned to normal. Two years later, he began smoking again, but has no relapse. Patient 3: A 21-year-old man was admitted to our hospital with pneumothorax. He had no history of smoking. A chest CT showed multiple cysts, and pulmonary eosinophilic granuloma was diagnosed by open lung biopsy. Diabetes insipidus was subsequently noted. Dyspnea persisted, and he recovered 4 months later after steroid treatment. He was without relapse 2 years later but the multiple cysts remained. We report three cases of pulmonary eosinophilic granuloma, and discuss their pertinent clinical features.
病例1：一名18岁女性因气胸入住我院。她无吸烟史。胸部CT显示多个囊肿，经开胸肺活检诊断为肺嗜酸性肉芽肿。3个月后未经治疗自行康复，当时的胸部CT检查结果正常。3年后她开始吸烟，并育有两个孩子。8年后未复发。病例2：一名23岁男性因气胸入住我院。他有吸烟史（吸烟指数=180）。胸部CT显示多个囊肿，经开胸肺活检诊断为肺嗜酸性肉芽肿。他戒烟，1个月后未经治疗康复，随后其CT检查结果恢复正常。两年后，他再次开始吸烟，但未复发。病例3：一名21岁男性因气胸入住我院。他无吸烟史。胸部CT显示多个囊肿，经开胸肺活检诊断为肺嗜酸性肉芽肿。随后发现尿崩症。呼吸困难持续存在，经类固醇治疗4个月后康复。两年后未复发，但多个囊肿仍然存在。我们报告了3例肺嗜酸性肉芽肿病例，并讨论了其相关临床特征。
