多巴胺在大鼠大脑皮层中的分布。
Distribution of dopamine in the rat cerebral cortex.
作者信息
Kehr W, Lindqvist M, Carlsson A
出版信息
J Neural Transm. 1976;38(3-4):173-80. doi: 10.1007/BF01249437.
The rat cerebral neocortex was sectioned by 3 transverse cuts and analyzed for dopamine and noradrenaline. Dopamine concentration decreased gradually from the rostral (97 +/- 4 ng/g) to the caudal (59 +/- 2 ng/g) end of the neocortex. Also, the noradrenaline concentration was highest in the rostral part (269 +/- 6 ng/g) and decreased gradually reaching a concentration of 238 +/- 3 ng/g in the caudal part. Since the quotient dopamine/noradrenaline showed similar changes in the neocortex parts investigated the data support the view that dopamine serves as a transmitter in cortical neurons apart from being a precursor for noradrenaline.
将大鼠大脑新皮质进行3次横向切割，并对多巴胺和去甲肾上腺素进行分析。多巴胺浓度从新皮质的吻侧端（97±4 ng/g）至尾侧端（59±2 ng/g）逐渐降低。此外，去甲肾上腺素浓度在吻侧部分最高（269±6 ng/g），并逐渐降低，在尾侧部分达到238±3 ng/g的浓度。由于在所研究的新皮质部分中多巴胺/去甲肾上腺素比值呈现相似变化，这些数据支持这样一种观点，即多巴胺除了作为去甲肾上腺素的前体之外，还作为皮质神经元中的一种神经递质。
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