• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

通过凝胶过滤法分离松果体提取物。V. 通过纸色谱法确定绵羊松果体中一种抑制垂体促性腺活性物质的位置。

Separation of pineal extracts by gelfiltration. V. Location by paper chromatography of a sheep pineal principle inhibiting hypophyseal gonadotropic activity.

作者信息

Moszkowska A, Hus-Citharel A, L'Héritier A, Zurburg W, Ebels I

出版信息

J Neural Transm. 1976;38(3-4):239-47. doi: 10.1007/BF01249441.

DOI:10.1007/BF01249441
PMID:956810
Abstract

Previously we were able to isolate by simple and mild methods from an aqueous sheep pineal extract an inhibiting principle action on the anterior hypophysis of male rats in vitro. This substance could be located by paper electrophoresis. In the present paper we describe the further purification of this active principle by paper chromatography in two different solvents. In two regions possessing a special fluorescence an inhibiting factor of the gonadotropic activity of the anterior pituitary was found in vitro.

摘要

此前，我们能够通过简单温和的方法，从羊松果体水提取物中分离出一种在体外对雄性大鼠垂体前叶有抑制作用的成分。这种物质可以通过纸电泳进行定位。在本文中，我们描述了通过在两种不同溶剂中进行纸色谱法对这种活性成分的进一步纯化。在两个具有特殊荧光的区域，发现了一种在体外对垂体促性腺活性有抑制作用的因子。

相似文献

1
Separation of pineal extracts by gelfiltration. V. Location by paper chromatography of a sheep pineal principle inhibiting hypophyseal gonadotropic activity.通过凝胶过滤法分离松果体提取物。V. 通过纸色谱法确定绵羊松果体中一种抑制垂体促性腺活性物质的位置。
J Neural Transm. 1976;38(3-4):239-47. doi: 10.1007/BF01249441.
2
Separation of pineal extracts by gelfiltration. III. Sheep pineal factors acting either on the hypothalamus, or on the anterior hypophysis of mice and rats in in vitro experiments.通过凝胶过滤法分离松果体提取物。III. 在体外实验中，绵羊松果体因子对小鼠和大鼠下丘脑或垂体前叶的作用
J Neural Transm. 1975;36(3-4):281-302. doi: 10.1007/BF01253130.
3
Some new aspects of a sheep pineal gonadotropic inhibiting activity in in vitro experiments.
Experientia. 1974 Aug 15;30(8):964-5. doi: 10.1007/BF01938389.
4
The influence of the pineal body on the gonadotropic function of the hypophysis.松果体对垂体促性腺功能的影响。
J Neurovisc Relat. 1971;0(0):suppl 10:160-76. doi: 10.1007/978-3-7091-4157-1_17.
5
Separation of pineal extracts by gelfiltration. II. Identification and isolation of two indoles from sheep pineal glands.通过凝胶过滤法分离松果体提取物。II. 从绵羊松果体中鉴定和分离出两种吲哚。
J Neural Transm. 1975;36(1):59-69. doi: 10.1007/BF01243438.
6
Lack of gonadotrophin-inhibiting activity of ovine pineal extracts.绵羊松果体提取物缺乏促性腺激素抑制活性。
J Reprod Fertil. 1970 Oct;23(1):161-3. doi: 10.1530/jrf.0.0230161.
7
A survey of the location, isolation and identification of indoles, pteridines and some unknown active substances in sheep pineals. The possible significance of pteridines for the neuroendocrine control of neoplastic growth.绵羊松果体中吲哚、蝶啶及一些未知活性物质的定位、分离与鉴定研究。蝶啶对肿瘤生长神经内分泌控制的可能意义。
J Neural Transm. 1980;49(1-2):87-105. doi: 10.1007/BF01249191.
8
[Purification of pineal antigonadotropic factor (author's transl)].[松果体抗促性腺激素因子的纯化（作者译）]
Ann Endocrinol (Paris). 1979;40(6):519-29.
9
[Effect of epithalamin on hypophyseal and ovarian gonadotropic function].[表皮生长因子对垂体和卵巢促性腺功能的影响]
Akush Ginekol (Mosk). 1980 Sep(9):15-8.
10
Studies on a high molecular weight luteinizing hormone release stimulating factor of the ovine pineal gland.
J Neural Transm. 1988;72(1):19-36. doi: 10.1007/BF01244629.

引用本文的文献

1
A survey of the location, isolation and identification of indoles, pteridines and some unknown active substances in sheep pineals. The possible significance of pteridines for the neuroendocrine control of neoplastic growth.绵羊松果体中吲哚、蝶啶及一些未知活性物质的定位、分离与鉴定研究。蝶啶对肿瘤生长神经内分泌控制的可能意义。
J Neural Transm. 1980;49(1-2):87-105. doi: 10.1007/BF01249191.
2
The effect of ovine pineal compounds prepared under red or green light on the activity of male rat anterior pituitaries in vitro.在红光或绿光下制备的绵羊松果体化合物对雄性大鼠垂体前叶体外活性的影响。
J Neural Transm. 1985;62(1-2):155-67. doi: 10.1007/BF01260424.
3

本文引用的文献

1
A fluorometric procedure for the measurement of tryptamine in tissues.一种用于测量组织中色胺的荧光测定法。
J Pharmacol Exp Ther. 1959 Nov;127:175-7.
2
A study of the antigonadotrophic action of synthetic arginine vasotocin.
Experientia. 1968 Jun 15;24(6):610-1. doi: 10.1007/BF02153804.
3
Radioimmunoassay for rat luteinizing hormone with antiovine LH serum and ovine LH-131-I.使用抗羊促黄体生成素血清和羊促黄体生成素-131碘进行大鼠促黄体生成素的放射免疫测定。
Proc Soc Exp Biol Med. 1968 Jul;128(3):807-11. doi: 10.3181/00379727-128-33129.
Separation of pineal extracts by gelfiltration. VI. Isolation and identification from sheep pineals of biopterin; comparison of the isolated compound with some synthetic pteridines and the biological activity in in vitro and in vivo bioassays.
通过凝胶过滤法分离松果体提取物。VI. 从绵羊松果体中分离并鉴定生物蝶呤；将分离出的化合物与一些合成蝶啶进行比较以及体外和体内生物测定中的生物活性。
J Neural Transm. 1977;40(3):205-20. doi: 10.1007/BF01300135.
4
A survey of some active sheep pineal fractions and a discussion on the possible significance of pteridines in those fractions in in vitro and in vivo assays.对一些活性绵羊松果体组分的调查以及关于这些组分中蝶啶在体外和体内试验中可能意义的讨论。
J Neural Transm. 1979;44(1-2):97-116. doi: 10.1007/BF01252705.
5
Ultrastructure of rat pinealocytes in vitro: influence of gonadotropic hormones and LH-RH.体外培养大鼠松果体细胞的超微结构：促性腺激素和促黄体生成激素释放激素的影响
Cell Tissue Res. 1978 Dec 29;195(3):547-56. doi: 10.1007/BF00233896.
6
A pharmacological and autoragiographic study on the ultrastructural localization of indoleamine synthesis in the rabbit pineal gland.家兔松果体中吲哚胺合成超微结构定位的药理学与放射自显影研究
Cell Tissue Res. 1977 Dec 13;185(2):199-214. doi: 10.1007/BF00220665.
4
Separation of pineal extracts on sephadex G-10. I. A spectrofluorimetric study of indoles in a cockerel pineal extract.松果体提取物在葡聚糖凝胶G - 10上的分离。I. 公鸡松果体提取物中吲哚的荧光光谱研究。
J Neurovisc Relat. 1970;32(1):65-73. doi: 10.1007/BF02324331.
5
The influence of the pineal body on the gonadotropic function of the hypophysis.松果体对垂体促性腺功能的影响。
J Neurovisc Relat. 1971;0(0):suppl 10:160-76. doi: 10.1007/978-3-7091-4157-1_17.
6
Separation of pineal extracts on Sephadex G-10. II. A spectrofluorimetric and thinlayer chromatographic study of indoles in a sheep pineal extract.
J Neurovisc Relat. 1972;32(14):270-81. doi: 10.1007/BF02327925.
7
Separation of pineal extracts by gelfiltration. I. Isolation from sheep pineals of a substance with special fluorescence characteristics.
J Neural Transm. 1974;35(2):117-24. doi: 10.1007/BF01250739.
8
Localization of a sheep pineal antigonadotropin.
Anal Biochem. 1973 Dec;56(2):546-65. doi: 10.1016/0003-2697(73)90220-0.
9
Some new aspects of a sheep pineal gonadotropic inhibiting activity in in vitro experiments.
Experientia. 1974 Aug 15;30(8):964-5. doi: 10.1007/BF01938389.
10
A new pteridine from Tetrahymena.一种来自四膜虫的新蝶啶。
J Biol Chem. 1968 Feb 25;243(4):826-33.