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内源性病毒基因与高蛋产量及对马立克氏病易感性或抗性的鸡的数量性状的关联

Association of endogenous viral genes with quantitative traits in chickens selected for high egg production and susceptibility or resistance to Marek's disease.

作者信息

Aggrey S E, Kuhnlein U, Gavora J S, Zadworny D

机构信息

Department of Animal Science, McGill University, Quebec, Canada.

出版信息

Br Poult Sci. 1998 Mar;39(1):39-41. doi: 10.1080/00071669889367.

DOI:10.1080/00071669889367
PMID:9568296
Abstract
  1. The association of endogenous viral (ev) genes with quantitative traits in 2 genetically distinct sets of White Leghorn strains were investigated. Strain S had been selected for susceptibility to Marek's disease (MD) whereas strain K had been selected for resistance to MD and high egg production and egg weight. 2. In all, 8 ev genes were typed. Ev10, ev19 and 'newB' occurred exclusively in strain S, 'newA' occurred only in strain K, and ev1, ev3, ev6 and ev8 occurred in both strains. 3. Whereas ev6 and ev8 were associated with reduction in egg production rate in strain S, in strain K, the presence of ev3 was associated with increased group specific antigen. 4. The genetic background of the chicken strain may play a role in the way certain ev genes affect traits. 5. It was thought that the position of ev genes on the chromosome may be important and their association with traits of economic importance make them potential genetic markers for uncovering quantitative trait loci.
摘要
  1. 研究了内源性病毒(ev)基因与两组遗传背景不同的白来航鸡品系数量性状之间的关联。品系S因对马立克氏病(MD)易感而被选育,而品系K因对MD具有抗性、产蛋量高和蛋重高而被选育。2. 总共对8个ev基因进行了分型。Ev10、ev19和“newB”仅出现在品系S中,“newA”仅出现在品系K中,ev1、ev3、ev6和ev8在两个品系中均有出现。3. 在品系S中,ev6和ev8与产蛋率降低有关,而在品系K中,ev3的存在与群体特异性抗原增加有关。4. 鸡品系的遗传背景可能在某些ev基因影响性状的方式中起作用。5. 人们认为,ev基因在染色体上的位置可能很重要,并且它们与经济重要性状的关联使其成为揭示数量性状基因座的潜在遗传标记。

相似文献

1
Association of endogenous viral genes with quantitative traits in chickens selected for high egg production and susceptibility or resistance to Marek's disease.内源性病毒基因与高蛋产量及对马立克氏病易感性或抗性的鸡的数量性状的关联
Br Poult Sci. 1998 Mar;39(1):39-41. doi: 10.1080/00071669889367.
2
Influence of Marek's disease virus strain AC-1 on cellular immunity in birds carrying endogenous viral genes.马立克氏病病毒AC-1株对携带内源性病毒基因禽类细胞免疫的影响。
Avian Dis. 1996 Jul-Sep;40(3):645-53.
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Influence of selection for egg production and Marek's disease resistance on the incidence of endogenous viral genes in White Leghorns.对白来航鸡产蛋性能和马立克氏病抗性的选择对其内源性病毒基因发生率的影响。
Poult Sci. 1989 Sep;68(9):1161-7. doi: 10.3382/ps.0681161.
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Genetic resistance to Marek's disease.对马立克氏病的遗传抗性
Curr Top Microbiol Immunol. 2001;255:121-41. doi: 10.1007/978-3-642-56863-3_5.
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Genetic variation in susceptibility to Marek's disease in a commercial broiler population.商业肉鸡群体中马立克氏病易感性的遗传变异。
Avian Dis. 2001 Apr-Jun;45(2):400-9.
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Notes on the mechanism of postvaccination immunity in Marek's disease.马立克氏病疫苗接种后免疫机制的笔记
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Studies on the role of macrophages in Marek's disease of the chicken.巨噬细胞在鸡马立克氏病中作用的研究。
J Reticuloendothel Soc. 1983 Oct;34(4):289-97.
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Transcriptional analysis of host responses to Marek's disease virus infection in genetically resistant and susceptible chickens.对基因抗性和易感鸡群中宿主对马立克氏病病毒感染反应的转录分析。
Anim Genet. 2008 Jun;39(3):232-40. doi: 10.1111/j.1365-2052.2008.01710.x. Epub 2008 Mar 26.

引用本文的文献

1
Characterization of Copy Number Variation's Potential Role in Marek's Disease.拷贝数变异在马立克氏病中潜在作用的特征分析
Int J Mol Sci. 2017 May 9;18(5):1020. doi: 10.3390/ijms18051020.
2
Virus and host genomic, molecular, and cellular interactions during Marek's disease pathogenesis and oncogenesis.马立克氏病发病机制和肿瘤发生过程中的病毒与宿主基因组、分子及细胞相互作用。
Poult Sci. 2016 Feb;95(2):412-29. doi: 10.3382/ps/pev369. Epub 2016 Jan 11.