Watanabe T, Murakami T, Okochi H, Kikuchi K, Furue M
Department of Dermatology, Tokyo University Branch Hospital, Japan.
Dermatology. 1998;196(2):256-9. doi: 10.1159/000017887.
A 54-year-old man presented with multiple annular plaques since infancy. During the intake of nifedipine and nitroglycerin over a period of 6 years, reddish, eruptive and ulcerative changes were seen in the pre-existing skin lesions on the penis, scrotum and legs. In addition to a typical cornoid lamella, histological examination revealed a band-like infiltration beneath the epidermis, liquefaction degeneration of the basal cell layer and subsequent coagulative necrosis of the keratinocytes. We review similar ulcerative types of porokeratosis in the literature and discuss the significance of our unusual case.
一名54岁男性自婴儿期起就出现多个环状斑块。在服用硝苯地平和硝酸甘油6年期间，其阴茎、阴囊和腿部原有的皮肤损害处出现了发红、发疹及溃疡改变。组织学检查除发现典型的鸡眼样板外，还显示表皮下带状浸润、基底细胞层液化变性以及随后角质形成细胞的凝固性坏死。我们回顾了文献中类似的溃疡性汗孔角化症类型，并讨论了我们这一罕见病例的意义。
