加拿大国家实验室（TRIUMF）调制质子束的相对生物效应。
The relative biological effectiveness of the modulated proton beam at TRIUMF.
作者信息
Nemoto K, Pickles T, Minchinton A I, Lam G K
机构信息
Department of Radiology, Tohoku University School of Medicine, Sendai, Japan.
出版信息
Radiat Med. 1998 Jan-Feb;16(1):43-6.
PURPOSE
The purpose of this study was to determine the relative biological effectiveness (RBE) of proton beam and to study its dependency on fraction number.
METHODS
The relative biological effectiveness (RBE) of fractionated protons compared with 60Co gamma-rays was investigated for the acute mouse skin reaction. The 80 MeV protons generated at the TRIUMF cyclotron were spread out from 7 to 25 mm to irradiate entire legs. One, two, four, and eight fractions were tested.
RESULTS
RBE values ranged from 1.15 to 1.24 for the acute skin reaction. Fraction dose dependence of RBEs was not observed.
目的
本研究的目的是确定质子束的相对生物效应（RBE），并研究其对分次照射次数的依赖性。
方法
研究了分次质子照射与60Coγ射线相比对小鼠急性皮肤反应的相对生物效应（RBE）。在TRIUMF回旋加速器产生的80 MeV质子在7至25 mm范围内分散，以照射整个腿部。测试了1、2、4和8次分次照射。
结果
急性皮肤反应的RBE值范围为1.15至1.24。未观察到RBE的分次剂量依赖性。
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