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大麻与脑功能。

Cannabis and brain function.

作者信息

Court J M

机构信息

Centre for Adolescent Health, Royal Children's Hospital, Parkville, Victoria, Australia.

出版信息

J Paediatr Child Health. 1998 Feb;34(1):1-5. doi: 10.1046/j.1440-1754.1998.00142.x.

DOI:10.1046/j.1440-1754.1998.00142.x
PMID:9568931
Abstract

Current literature and practice experience has been reviewed to clarify what is known about the effects of cannabis on brain function, the risk that cannabis use may pose for young people during their adolescence, and risk factors within the individual or their environment that may predispose to long-term abuse and dependence. There is sound evidence that cannabis intoxication has an adverse effect on cognitive function and behaviour, and may, in vulnerable individuals, lead to a psychotic reaction. Regular use may have an adverse effect on learning, with possible mid- to long-term psychological and cognitive impairment. Heavy use may lead to emotional dependence with consequent social and psychological dysfunction. Intervention strategies must go beyond the conventional education and public health measures that appear to have been unsuccessful so far in influencing cannabis use in teenagers. Such strategies may more usefully aim at assessment of risk factors in individuals and groups for dependence on the drug, and the combined and cooperative intervention of parents, schools, health professionals and teenagers themselves.

摘要

对当前的文献和实践经验进行了综述,以阐明关于大麻对脑功能的影响、青少年使用大麻可能面临的风险,以及个体或其环境中可能易导致长期滥用和依赖的风险因素。有充分证据表明,大麻中毒会对认知功能和行为产生不利影响,并且在易感个体中可能导致精神病反应。经常使用大麻可能会对学习产生不利影响,可能导致中长期的心理和认知损害。大量使用大麻可能会导致情感依赖,进而造成社会和心理功能障碍。干预策略必须超越传统的教育和公共卫生措施,这些措施迄今为止在影响青少年使用大麻方面似乎并不成功。此类策略可能更有效地针对评估个体和群体对该药物的依赖风险因素,以及家长、学校、卫生专业人员和青少年自身的联合与合作干预。

相似文献

1
Cannabis and brain function.大麻与脑功能。
J Paediatr Child Health. 1998 Feb;34(1):1-5. doi: 10.1046/j.1440-1754.1998.00142.x.
2
Effects of Cannabis Use on Human Behavior, Including Cognition, Motivation, and Psychosis: A Review.大麻使用对人类行为的影响,包括认知、动机和精神病:综述。
JAMA Psychiatry. 2016 Mar;73(3):292-7. doi: 10.1001/jamapsychiatry.2015.3278.
3
Adverse effects of cannabis.大麻的不良反应。
Prescrire Int. 2011 Jan;20(112):18-23.
4
Psychiatric effects of cannabis.大麻的精神影响。
Br J Psychiatry. 2001 Feb;178:116-22. doi: 10.1192/bjp.178.2.116.
5
[Cognitive and psychotic effects after cessation of chronic cannabis use].[长期使用大麻戒断后的认知和精神影响]
Ned Tijdschr Geneeskd. 1998 May 2;142(18):1047-8.
6
Adolescent exposure to cannabis as a risk factor for psychiatric disorders.青少年接触大麻作为精神障碍的风险因素。
J Psychopharmacol. 2012 Jan;26(1):177-88. doi: 10.1177/0269881111405362. Epub 2011 Jul 18.
7
Long lasting consequences of cannabis exposure in adolescence.青少年接触大麻的长期后果。
Mol Cell Endocrinol. 2008 Apr 16;286(1-2 Suppl 1):S108-13. doi: 10.1016/j.mce.2008.02.003. Epub 2008 Feb 13.
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What every adolescent needs to know: cannabis can cause psychosis.每个青少年都应该知道:大麻可能导致精神错乱。
J Psychosom Res. 2010 Dec;69(6):533-9. doi: 10.1016/j.jpsychores.2010.04.002. Epub 2010 May 20.
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Acute and Chronic Effects of Cannabinoids on Human Cognition-A Systematic Review.大麻素对人类认知的急性和慢性影响——系统评价。
Biol Psychiatry. 2016 Apr 1;79(7):557-67. doi: 10.1016/j.biopsych.2015.12.002. Epub 2015 Dec 8.
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[Cognitive and psychotic effects after cessation of chronic cannabis use].[长期使用大麻戒断后的认知和精神症状]
Ned Tijdschr Geneeskd. 1998 Mar 7;142(10):504-8.

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Rages and refusals. Managing the many faces of adolescent anxiety.
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Can Fam Physician. 2001 May;47:1023-30.