McNamara F, Sullivan C E
National SIDS Council David Read Paediatric Sleep Disorders Centre, Royal Alexandra Hospital for Children, Camperdown, NSW, Australia.
J Paediatr Child Health. 1998 Feb;34(1):37-43. doi: 10.1046/j.1440-1754.1998.00150.x.
The evolution of sleep-disordered breathing and sleeping patterns in a group of high-risk infants was studied throughout the first year of life.
Eleven infants with documented sleep apnoea underwent overnight polysomnographic studies at monthly intervals to 6 months, then at 9 and 12 months of age.
All infants had central apnoea and obstructive events recorded on their initial sleep studies. The sleep-disordered breathing in these infants was associated with disturbed sleeping patterns. The amount of rapid eye movement (REM) sleep recorded in each study was inversely proportional to the amount of apnoea. The amount of apnoea and sleep disturbances were highest at 2 months of age and then progressively improved and obstructive events resolved by 1 year of age.
The respiratory abnormalities and sleep disturbances peaked in severity at the age reported to have the highest incidence of sudden infant death syndrome (SIDS) and may have implications for its aetiology.
研究一组高危婴儿在出生后第一年睡眠呼吸障碍和睡眠模式的演变。
11名有记录的睡眠呼吸暂停婴儿每月进行一次夜间多导睡眠图研究，直至6个月大，然后在9个月和12个月大时进行研究。
所有婴儿在初次睡眠研究中均记录到中枢性呼吸暂停和阻塞性事件。这些婴儿的睡眠呼吸障碍与睡眠模式紊乱有关。每次研究中记录的快速眼动（REM）睡眠量与呼吸暂停量成反比。呼吸暂停和睡眠障碍的量在2个月大时最高，然后逐渐改善，阻塞性事件在1岁时消失。
呼吸异常和睡眠障碍的严重程度在据报道婴儿猝死综合征（SIDS）发病率最高的年龄达到峰值，可能对其病因学有影响。
