Dunning D, Monnet E, Orton E C, Salman M D
Department of Clinical Sciences, Veterinary Teaching Hospital, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523-1620, USA.
J Am Vet Med Assoc. 1998 Apr 15;212(8):1276-80.
To determine factors associated with disease-free interval and survival time for dogs with pericardial effusion.
Retrospective study.
46 dogs.
Signalment, history, results of physical examination, electrocardiography, echocardiography, and thoracic radiography; disease-free interval; and survival time were obtained from medical records or telephone conversations with owners and referring veterinarians.
Dogs that had ascites at the time of the initial physical examination were significantly less likely, and dogs that had evidence of pulmonary metastases on thoracic radiographs or that had echocardiographic evidence of a right atrial mass were significantly more likely, to have died of pericardial effusion or the underlying cause of effusion than were dogs that did not. Median survival time was 15.3 months for dogs with idiopathic pericardial effusion, 16 days for dogs with hemangiosarcoma, and 13.6 months for dogs with mesothelioma. Dogs that had a nonspecific extracardiac mass and underwent pericardiectomy were significantly less likely to have had recurrence of signs than were dogs that did not. However, dogs with mesothelioma or hemangiosarcoma that underwent pericardiectomy did not have a significantly different risk of recurrence of signs or survival time, compared with dogs that did not.
Results suggest that pericardiectomy will not affect risk of recurrence or survival time in dogs with pericardial effusion secondary to hemangiosarcoma or mesothelioma. However, pericardiectomy is still needed to differentiate dogs with neoplastic pericardial effusion from dogs with idiopathic pericardial effusion.
确定与心包积液犬无病生存期和生存时间相关的因素。
回顾性研究。
46只犬。
从病历或与犬主及转诊兽医的电话交谈中获取信号、病史、体格检查结果、心电图、超声心动图和胸部X光检查结果；无病生存期；以及生存时间。
初次体格检查时有腹水的犬死于心包积液或积液潜在病因的可能性显著低于无腹水的犬，胸部X光片有肺转移证据或超声心动图有右心房肿块证据的犬死于心包积液或积液潜在病因的可能性显著高于无相关证据的犬。特发性心包积液犬的中位生存时间为15.3个月，血管肉瘤犬为16天，间皮瘤犬为13.6个月。有非特异性心外肿块并接受心包切除术的犬出现体征复发的可能性显著低于未接受心包切除术的犬。然而，与未接受心包切除术的犬相比，患有间皮瘤或血管肉瘤且接受心包切除术的犬出现体征复发的风险或生存时间并无显著差异。
结果表明，心包切除术不会影响血管肉瘤或间皮瘤继发心包积液犬的复发风险或生存时间。然而，仍需要进行心包切除术以区分肿瘤性心包积液犬和特发性心包积液犬。
