Gartenschläger M, Schweden F, Gast K, Westermeier T, Kauczor H, von Zitzewitz H, Thelen M
Department of Diagnostic Radiology, J. Gutenberg University, University Hospital, Langenbeckstrasse 1, D-55 131 Mainz, Germany.
Eur Radiol. 1998;8(4):609-14. doi: 10.1007/s003300050445.
The purpose of the study was the evaluation of low-dose spiral CT in the detection and assessment of contours of pulmonary nodules. In a prospective investigation 71 consecutive chest CT examinations were acquired both at 30 and 200 mA. Films were interpreted independently by two radiologists. According to the size, nodules were divided into four categories: </= 3, 4-5, 6-10, and > 10 mm; nodule shape was registered. With both protocols, 240 nodules were detected. The correlation coefficient for both methods was 0.89. Discrepancies were found most frequently in nodules near to pulmonary vessels. Nodule size estimation did not differ more than one size category. Eight spiculated nodules were identified by both techniques. Low-dose spiral CT of the chest has a high sensitivity in the detection of pulmonary nodules. If clinical circumstances require dose minimization, low-dose spiral CT may be advocated as an alternative screening method to conventional dose spiral CT.
本研究的目的是评估低剂量螺旋CT在检测和评估肺结节轮廓方面的作用。在一项前瞻性研究中，连续71例胸部CT检查分别在30 mA和200 mA条件下进行。两位放射科医生独立解读影像。根据大小，结节分为四类：≤3 mm、4 - 5 mm、6 - 10 mm和>10 mm；记录结节形状。两种方案均检测到240个结节。两种方法的相关系数为0.89。差异最常出现在靠近肺血管的结节中。结节大小估计差异不超过一个尺寸类别。两种技术均识别出8个有毛刺的结节。胸部低剂量螺旋CT在检测肺结节方面具有较高的敏感性。如果临床情况需要将剂量最小化，低剂量螺旋CT可作为传统剂量螺旋CT的替代筛查方法。
