Walsh V, Ellison A, Battelli L, Cowey A
Department of Experimental Psychology, University of Oxford, UK.
Proc Biol Sci. 1998 Mar 22;265(1395):537-43. doi: 10.1098/rspb.1998.0328.
Transcranial magnetic stimulation (TMS) can be used to simulate the effects of highly circumscribed brain damage permanently present in some neuropsychological patients, by reversibly disrupting the normal functioning of the cortical area to which it is applied. By using TMS we attempted to recreate deficits similar to those reported in a motion-blind patient and to assess the specificity of deficits when TMS is applied over human area V5. We used six visual search tasks and showed that subjects were impaired in a motion but not a form 'pop-out' task when TMS was applied over V5. When motion was present, but irrelevant, or when attention to colour and form were required, TMS applied to V5 enhanced performance. When attention to motion was required in a motion-form conjunction search task, irrespective of whether the target was moving or stationary, TMS disrupted performance. These data suggest that attention to different visual attributes involves mutual inhibition between different extrastriate visual areas.
经颅磁刺激（TMS）可用于模拟一些神经心理学患者中永久存在的高度局限性脑损伤的影响，方法是通过可逆地破坏其应用部位的皮质区域的正常功能。通过使用TMS，我们试图重现类似于运动盲患者所报告的缺陷，并评估在人类V5区域应用TMS时缺陷的特异性。我们使用了六个视觉搜索任务，结果表明，当在V5区域应用TMS时，受试者在运动“跳出”任务中受损，但在形状“跳出”任务中未受损。当存在运动但不相关时，或者当需要关注颜色和形状时，应用于V5的TMS会提高表现。在运动-形状联合搜索任务中，当需要关注运动时，无论目标是移动还是静止，TMS都会干扰表现。这些数据表明，对不同视觉属性的关注涉及不同纹外视觉区域之间的相互抑制。
