Gutman P D, Williams J P, Dveksler G S, Hoffmeister K, Cotelingam J D
Department of Laboratory Medicine, National Naval Medical Center, Bethesda, Maryland, USA.
Gynecol Oncol. 1998 Mar;68(3):288-92. doi: 10.1006/gyno.1997.4918.
Although secondary involvement of the female genital tract occurs in up to 40% of cases of disseminated lymphomas, lymphomas presenting with primary female genital tract symptomatology are very unusual. We report a case of T-cell-rich B-cell lymphoma (TCRBCL) arising in the uterine corpus of a 57-year-old female who carried an intrauterine contraceptive device (IUD) for over 20 years. Malignant lymphoid cells expressed the Epstein-Barr virus (EBV) late membrane protein (LMP), a feature described in TCRBCL but not previously reported in primary uterine lymphomas. To our knowledge, this is the first reported case of a TCRBCL of the uterus.
尽管在高达40%的播散性淋巴瘤病例中会出现女性生殖道的继发性受累，但以原发性女性生殖道症状表现的淋巴瘤非常罕见。我们报告一例发生在一名57岁女性子宫体的富于T细胞的B细胞淋巴瘤（TCRBCL），该女性放置宫内节育器（IUD）超过20年。恶性淋巴样细胞表达爱泼斯坦-巴尔病毒（EBV）晚期膜蛋白（LMP），这是TCRBCL中描述的一个特征，但此前在原发性子宫淋巴瘤中未见报道。据我们所知，这是首例报道的子宫TCRBCL病例。
