Take H, Kubota K, Fukuda T, Shinonome S, Ishikawa O, Shirakura T
Department of Medicine, Kusatsu Branch Hospital, Gunma University School of Medicine, Japan.
Am J Hematol. 1996 Jul;52(3):221-3. doi: 10.1002/(SICI)1096-8652(199607)52:3<221::AID-AJH16>3.0.CO;2-I.
A 74-year-old Japanese man presented with systemic lymphadenopathy, hepatosplenomegaly, and erythroderma in December 1991. A characteristic pattern of anti-EBV antibodies was suggestive of latent EBV infection. A skin tumor biopsied in April 1993 contained biclonal EBV genomes diffusely in the infiltrate of polyclonal T cells and monoclonal B cells. The clinical course was rather mild in contrast to that of classical EBV-associated disorders. Our case was considered a rare indolent type of EBV-associated T-cell-rich B-cell lymphoma of the skin.
1991年12月，一名74岁的日本男性出现全身淋巴结病、肝脾肿大和红皮病。抗EBV抗体的特征性模式提示EBV潜伏感染。1993年4月活检的皮肤肿瘤在多克隆T细胞和单克隆B细胞浸润中弥漫性地含有双克隆EBV基因组。与经典的EBV相关疾病相比，临床病程相当轻微。我们的病例被认为是一种罕见的惰性类型的皮肤EBV相关富含T细胞的B细胞淋巴瘤。
