Müller-Jensen A, Zschocke S
Neurologische Universitätsklinik, Hamburg, G.F.R.
Electroencephalogr Clin Neurophysiol. 1979 Aug;47(2):239-42. doi: 10.1016/0013-4694(79)90224-4.
A report of first results of a simultaneous analysis of the phasic pupillary light reflex and visual evoked potentials (VEP). It is shown that combination of pupillography with VEP analysis can be of some use in the diagnosis of conductive defects of the optic nerve (e.g. optic neuritis). Furthermore, the simultaneous analysis allows distinction between subclinical disturbances of the afferent and efferent arcs of the pupillary light reflex. Assuming a lesion of the afferent arc secondary to damage to the optic nerve, an increase of both the pupillomotor and the VEP latencies is seen. With lesions of the efferent arc (e.g. in the case of a third nerve palsy) only the pupillomotor latency is altered. Potentialities and disadvantages of the method are discussed.
一份关于同时分析瞳孔对光反射相位和视觉诱发电位（VEP）的初步结果报告。结果表明，瞳孔描记术与VEP分析相结合在诊断视神经传导缺陷（如视神经炎）方面可能具有一定作用。此外，同时分析能够区分瞳孔对光反射传入和传出弧的亚临床干扰。假设视神经损伤继发传入弧病变，可观察到瞳孔运动和VEP潜伏期均增加。而对于传出弧病变（如动眼神经麻痹的情况），仅瞳孔运动潜伏期会改变。本文还讨论了该方法的潜力和缺点。
