Kusama M, Kimura K, Koyanagi Y, Kaise H, Arima M, Satoh Y, Murata J, Matsunaga T
Dept. of Surgery, Tokyo Medical College.
Gan To Kagaku Ryoho. 1993 Mar;20(4):521-4.
A 55-year-old female was admitted for right breast tumor with multiple bilateral lung metastases. Modified radical mastectomy (Auchincloss method) was carried out. And the combination chemoendocrine therapy was undertaken using CPA 100 mg p.o. days 1-18, THP 40 mg i.v. days 1, 8, 5-FU 500 mg i.v. days 1, 8 and MPA 1,200 mg p.o. daily. One month later, the lung metastases completely disappeared on chest CT gram. Nine courses of chemotherapy with the same drugs were undertaken intravenously every four weeks. This therapy has been continuously effective for one and half years now. These results suggested the importance of a severe adjuvant therapy for the initial phase of advanced breast cancer.
一名55岁女性因右乳肿瘤伴双侧肺多发转移入院。行改良根治性乳房切除术（Auchincloss法）。采用环磷酰胺100mg口服，第1 - 18天；吡柔比星40mg静脉注射，第1、8天；氟尿嘧啶500mg静脉注射，第1、8天；甲羟孕酮1200mg口服，每日，进行联合化疗内分泌治疗。1个月后，胸部CT显示肺转移灶完全消失。每4周静脉进行9个疗程相同药物的化疗。该治疗至今已持续有效1年半。这些结果提示了强化辅助治疗在晚期乳腺癌初始阶段的重要性。
