Kimura M, Hagiwara S, Hirose K, Shimokawa Y, Iwai K, Uemura K
Dept. of Surgery, Health Insurance Hitoyoshi General Hospital.
Gan To Kagaku Ryoho. 1994 Oct;21(14):2505-8.
We reported 2 cases of breast cancer with lymph node metastasis treated with CAF (cyclophosphamide, adriamycin, 5-fluorouracil) and medroxyprogesterone acetate (MPA). Case 1 was stage IV [T4b, N3 M1 (lung)] and case 2 was stage IIIa (T1, N2, M0). The two cases responded well to CAF and MPA therapy in local and systemic lesions, and then underwent radiotherapy and lymph node resection without mastectomy. After these treatments, both cases were thought to be disease-free. Major side effects were allopecia, obesity, and leukopenia. These results suggest that combination chemoendotherapy, radiotherapy, and surgery can be utilized for most patients with moderately advanced breast cancer.
我们报告了2例伴有淋巴结转移的乳腺癌患者，她们接受了CAF（环磷酰胺、阿霉素、5-氟尿嘧啶）和醋酸甲羟孕酮（MPA）治疗。病例1为IV期[T4b，N3 M1（肺）]，病例2为IIIa期（T1，N2，M0）。这两例患者的局部和全身病灶对CAF和MPA治疗反应良好，随后未行乳房切除术，而是接受了放疗和淋巴结切除术。经过这些治疗后，两例患者均被认为无疾病。主要副作用为脱发、肥胖和白细胞减少。这些结果表明，联合化疗、放疗和手术可用于大多数中晚期乳腺癌患者。
