酿酒酵母YCC5（YCL025c）基因编码一种氨基酸通透酶Agp1，该酶可转运天冬酰胺和谷氨酰胺。
The Saccharomyces cerevisiae YCC5 (YCL025c) gene encodes an amino acid permease, Agp1, which transports asparagine and glutamine.
作者信息
Schreve J L, Sin J K, Garrett J M
机构信息
Department of Biology, Hamilton College, Clinton, New York 13323, USA.
出版信息
J Bacteriol. 1998 May;180(9):2556-9. doi: 10.1128/JB.180.9.2556-2559.1998.
Abstract
The yeast YCC5 gene encodes a putative amino acid permease and is homologous to GNP1 (encoding a high-affinity glutamine permease). Using strains with disruptions in the genes for multiple permeases, we demonstrated that Ycc5 (which we have renamed Agp1) is involved in the transport of asparagine and glutamine, performed a kinetic analysis of this activity, and showed that AGP1 expression is subject to nitrogen repression.
摘要
酵母YCC5基因编码一种假定的氨基酸通透酶，与GNP1（编码一种高亲和力谷氨酰胺通透酶）同源。我们使用多个通透酶基因被破坏的菌株，证明Ycc5（我们已将其重新命名为Agp1）参与天冬酰胺和谷氨酰胺的转运，对该活性进行了动力学分析，并表明AGP1的表达受氮阻遏。
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