Seĭfulla R D
Eksp Klin Farmakol. 1998 Jan-Feb;61(1):3-12.
The problem of pharmacological correction of working capacity and rehabilitation after exhausting physical exertion is discussed from the standpoint of current advances and detection of factors limiting man's working capacity. The removal of factors interfering with the development of optimal possibilities of man through the effect of medicinal drugs is considered. The article discusses the energy sources providing for the performance of physical work differing in power and duration in accordance with the specificity of a type of sports as a most convenient model for studying adaptation to physical exertion. Factors limiting the working capacity of athletes are classified on the basis of current advances in biochemistry and physiology. All pharmacological agents influencing human working capacity are classified according to the potency zones determining the supply of energy. Pharmacological monitoring of man's capacity for work is in fact disclosure of factors limiting it and their pharmacological correction. This allows planning of the means for excluding the use of dope drugs in sports medicine and scientifically substantiated use of drugs in heavy branches of industry, for promoting climato-zone adaptation, and in extreme conditions. It is shown that the use of strongly active drugs is not necessary because a large reserve is available of drugs of plant and animal origin possessing much lesser side effects.
从当前进展以及对限制人类工作能力因素的检测角度，探讨了在极度体力消耗后对工作能力进行药理学矫正及康复的问题。考虑了通过药物作用消除干扰人类发展最佳潜能的因素。文章以作为研究对体力消耗适应的最便捷模型的运动项目特异性，讨论了根据体力工作的功率和持续时间不同而提供能量的能源。基于生物化学和生理学的当前进展，对限制运动员工作能力的因素进行了分类。所有影响人类工作能力的药物制剂都根据决定能量供应的效能区域进行了分类。对人类工作能力的药理学监测实际上是对限制其能力的因素及其药理学矫正的揭示。这有助于规划在运动医学中排除使用兴奋剂药物的方法，以及在重工业部门科学合理地使用药物，以促进气候带适应和在极端条件下使用。结果表明，没有必要使用强效药物，因为有大量植物和动物来源的药物储备，其副作用要小得多。
