Kretschmann U, Schlote T, Stübiger N, Gendo K, Hipp E, Zrenner E
Abteilung Pathophysiologie des Sehens und Neuro-Ophthalmologie, Universitäts-Augenklinik Tübingen.
Klin Monbl Augenheilkd. 1998 Feb;212(2):93-100. doi: 10.1055/s-2008-1034840.
Multifocal electroretinography allows physiological mapping of the central retina. The purpose of this study was to describe the spatial distribution of ERG-activity in patients with impairment of macular function which usually do not exhibit a pathologic Ganzfeld-ERG.
6 patients with macular lesions due to uveitis (4), retinitis centralis serosa (1), and contusio bulbi (1) were examined using the multifocal ERG technique.
In normal volunteers the response density of the multifocal ERG decreased with eccentricity according to cone density distribution. In eyes with impaired central vision the foveal and macular responses were markedly diminished while surrounding signals were of normal or moderately decreased amplitudes.
With the multifocal ERG disturbances of macular function due to oedema and secondary structural changes were detected in the presented cases and the extension of the central lesions was estimated.
多焦视网膜电图可对中央视网膜进行生理图谱绘制。本研究的目的是描述黄斑功能受损患者中视网膜电图活性的空间分布,这些患者通常不表现出病理性全视野视网膜电图。
使用多焦视网膜电图技术对6例因葡萄膜炎(4例)、中心性浆液性脉络膜视网膜病变(1例)和眼球挫伤(1例)导致黄斑病变的患者进行了检查。
在正常志愿者中,多焦视网膜电图的反应密度根据视锥细胞密度分布随离心率降低。在中心视力受损的眼睛中,中央凹和黄斑反应明显减弱,而周围信号的振幅正常或中度降低。
在本研究病例中,通过多焦视网膜电图检测到了由于水肿和继发性结构变化导致的黄斑功能障碍,并估计了中央病变的范围。