Kretschmann U, Gendo K, Wilhelm H, Schiefer U, Hettesheimer H, Zrenner E
Universitäts-Augenklinik, Abteilung für Pathophysiologie des Sehens und Neuro-Ophthalmologie, Tübingen.
Klin Monbl Augenheilkd. 1998 Jan;212(1):40-9. doi: 10.1055/s-2008-1034830.
Multifocal electroretinography allows simultaneous recording of 61 focal electroretinographic signals from the retina of the posterior pole. The function of the outer retinal layers can be mapped for a visual field of 30.5 degrees radius. We herein describe the topography of such potentials in patients with hemianopic and concentric visual field defects.
Six patients with visual field defects caused by chorioretinal and central visual pathways diseases were examined using multifocal ERG.
In 30 normal volunteers in the entire 30 degrees visual field clear signals were obtained. In the patients with visual field defects caused by retinal diseases in areas with reduced light sensitivity diminished electroretinographical activity was found. In contrast, in patients with bitemporal hemianopsia due to a chiasmal lesion no correlation between visual field and magnitude of focal ERGs was seen.
In retinal disorders defects in multifocal ERG presented the similar pattern as scotomata in perimetry. The patient with visual field defects due to disturbances in the chiasma exhibited a normal ERG-topography. In patients with visual field defects multifocal ERG supported differentiation of the location of the lesion.
多焦视网膜电图可同时记录来自后极部视网膜的61个局部视网膜电图信号。可绘制出半径为30.5度视野范围内的外层视网膜功能图。我们在此描述偏盲和同心性视野缺损患者此类电位的地形图。
对6例由脉络膜视网膜和中枢视觉通路疾病导致视野缺损的患者进行了多焦视网膜电图检查。
在30名正常志愿者中，在整个30度视野范围内均获得了清晰的信号。在视网膜疾病导致视野缺损且光敏感度降低的区域，发现视网膜电图活动减弱。相比之下，在因视交叉病变导致双颞侧偏盲的患者中，未观察到视野与局部视网膜电图幅值之间存在相关性。
在视网膜疾病中，多焦视网膜电图的缺损呈现出与视野检查中暗点相似的模式。因视交叉紊乱导致视野缺损的患者表现出正常的视网膜电图地形图。在视野缺损患者中，多焦视网膜电图有助于病变部位的鉴别。
