放射免疫测定法作为一种测定血清庆大霉素水平的改进方法。

Radioimmunoassay as an improved method for measurement of serum levels of gentamicin.

作者信息

Longmore P, Atkins R C, Casley D, Johnston C I

出版信息

Med J Aust. 1976 May 15;1(20):738-40. doi: 10.5694/j.1326-5377.1976.tb141020.x.

DOI:10.5694/j.1326-5377.1976.tb141020.x

Abstract

A radioimmunoassay is described for the measurement of serum concentrations of gentamicin. This radioimmunoassay is more rapid, more specific and more accurate than microbiological assays. Knowledge of serum levels of gentamicin assists the clinician in regulating drug dosage to obtain an optimal therapeutic effect, and yet avoid toxic serum levels.

摘要

本文描述了一种用于测定血清中庆大霉素浓度的放射免疫分析法。这种放射免疫分析法比微生物学测定法更快速、更特异、更准确。了解血清中庆大霉素的水平有助于临床医生调整药物剂量，以获得最佳治疗效果，同时避免血清药物水平过高产生毒性。