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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Clin Exp Pharmacol Physiol. 1977 Nov-Dec;4(6):525-32. doi: 10.1111/j.1440-1681.1977.tb02682.x.

A radioimmunoassay is described for the measurement of gentamicin in serum or plasma. 2. The assay technique uses a tracer labelled with iodine-125 rather than tritium, and has advantages over previously reported radioimmunoassay methods (Longmore et al., 1976; Lewis, Nelson & Elder, 1972) with regard to rapidity, precision and simplicity of preparation of labelled gentamicin. 3. The iodination technique is simple and gives tracer in high yield, at high specific activity, and with complete immunological identity to unlabelled gentamicin. 4. There is a significant correlation between results obtained by this technique and by a microbial assay method but the radioimmunoassay is more rapid, specific and accurate.

本文描述了一种用于测定血清或血浆中庆大霉素的放射免疫分析法。2. 该分析技术使用碘-125标记的示踪剂而非氚，在标记庆大霉素的制备速度、精密度和简便性方面，比先前报道的放射免疫分析方法（Longmore等人，1976年；Lewis、Nelson和Elder，1972年）具有优势。3. 碘化技术简单，能高产率地获得示踪剂，其比活度高，且与未标记的庆大霉素具有完全相同的免疫特性。4. 该技术获得的结果与微生物分析法获得的结果之间存在显著相关性，但放射免疫分析法更快速、特异且准确。

Clin Exp Pharmacol Physiol. 1977 Nov-Dec;4(6):525-32. doi: 10.1111/j.1440-1681.1977.tb02682.x.

A radioimmunoassay is described for the measurement of gentamicin in serum or plasma. 2. The assay technique uses a tracer labelled with iodine-125 rather than tritium, and has advantages over previously reported radioimmunoassay methods (Longmore et al., 1976; Lewis, Nelson & Elder, 1972) with regard to rapidity, precision and simplicity of preparation of labelled gentamicin. 3. The iodination technique is simple and gives tracer in high yield, at high specific activity, and with complete immunological identity to unlabelled gentamicin. 4. There is a significant correlation between results obtained by this technique and by a microbial assay method but the radioimmunoassay is more rapid, specific and accurate.

本文描述了一种用于测定血清或血浆中庆大霉素的放射免疫分析法。2. 该分析技术使用碘-125标记的示踪剂而非氚，在标记庆大霉素的制备速度、精密度和简便性方面，比先前报道的放射免疫分析方法（Longmore等人，1976年；Lewis、Nelson和Elder，1972年）具有优势。3. 碘化技术简单，能高产率地获得示踪剂，其比活度高，且与未标记的庆大霉素具有完全相同的免疫特性。4. 该技术获得的结果与微生物分析法获得的结果之间存在显著相关性，但放射免疫分析法更快速、特异且准确。