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超重与市中心黑人及西班牙裔儿童更严重的哮喘症状之间的关联。

Association of being overweight with greater asthma symptoms in inner city black and Hispanic children.

作者信息

Luder E, Melnik T A, DiMaio M

机构信息

Jack and Lucy Clark Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029, USA.

出版信息

J Pediatr. 1998 Apr;132(4):699-703. doi: 10.1016/s0022-3476(98)70363-4.

DOI:10.1016/s0022-3476(98)70363-4
PMID:9580773
Abstract

OBJECTIVE

To determine whether the weight status of inner city black and Hispanic children with asthma differs from that of their peers and to assess whether overweight asthmatic children experience greater asthma symptoms.

STUDY DESIGN

A cross-sectional study in an ambulatory chest clinic of an inner city medical center.

METHODS

We studied black and Hispanic children aged 2 to 18 years (n = 209) with the single diagnosis of asthma. The peer control subjects consisted of a sample of black and Hispanic children aged 6 to 13 years (n = 1017), enrolled in the New York City schools. Asthma symptoms, the number of asthma medications prescribed, and peak expiratory flow rate (PEFR) measurements were used to classify asthma severity and relate to body mass index (BMI). Bivariate categorical analysis and chi 2 tests were performed to examine the relationship between high BMI and the individual measures of asthma severity.

RESULTS

The prevalence of overweight was significantly higher in children with moderate to severe asthma than in their peers. The risk of overweight based on a BMI in the 85th percentile or greater was significantly associated with the following measures of asthma severity: (1) the number of school days missed per year; (2) a PEFR less than or equal to 60% of the predicted PEFR; and (3) the number of asthma medications prescribed.

CONCLUSIONS

The prevalence of overweight was significantly higher in children with moderate to severe asthma than in their peers, and being overweight was associated with significantly more severe asthma symptoms. Further studies in overweight asthmatic children are needed, including the effect of weight loss on lung function and other markers of asthma severity.

摘要

目的

确定市中心区患哮喘的黑人和西班牙裔儿童的体重状况是否与其同龄人不同,并评估超重的哮喘儿童是否有更严重的哮喘症状。

研究设计

在市中心区医疗中心的门诊胸部诊所进行的一项横断面研究。

方法

我们研究了2至18岁(n = 209)仅诊断为哮喘的黑人和西班牙裔儿童。对照同龄人样本为纽约市学校中6至13岁(n = 1017)的黑人和西班牙裔儿童。哮喘症状、所开哮喘药物的数量以及呼气峰值流速(PEFR)测量值被用于对哮喘严重程度进行分类,并与体重指数(BMI)相关联。进行双变量分类分析和卡方检验以检查高BMI与哮喘严重程度的各项指标之间的关系。

结果

中度至重度哮喘儿童的超重患病率显著高于其同龄人。基于BMI处于第85百分位或更高水平的超重风险与以下哮喘严重程度指标显著相关:(1)每年缺课天数;(2)PEFR小于或等于预测PEFR的60%;(3)所开哮喘药物的数量。

结论

中度至重度哮喘儿童的超重患病率显著高于其同龄人,且超重与更严重的哮喘症状显著相关。需要对超重的哮喘儿童进行进一步研究,包括体重减轻对肺功能和哮喘严重程度的其他指标的影响。

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