Gennuso J, Epstein L H, Paluch R A, Cerny F
Department of Pediatrics, State University of New York at Buffalo, 14260, USA.
Arch Pediatr Adolesc Med. 1998 Dec;152(12):1197-200. doi: 10.1001/archpedi.152.12.1197.
To investigate the relationship between asthma and obesity in children and adolescents.
Medical record review.
Urban community health center.
One hundred seventy-one children aged 4 to 16 years, 85 with asthma and 86 nonasthmatic controls.
Diagnosis of asthma, age, and sex-adjusted body mass index (weight in kilograms divided by the square of the height in meters).
Seventy-eight percent of the sample was Hispanic, 17% was African American, 2% were white, and 3% were other minorities. There were significantly more children with asthma (30.6%) who were very obese (> or =95th body mass index percentile) compared with controls (11.6%) (P=.004). Children with asthma were also significantly more overweight than controls (mean+/-SD, 22.5%+/-28.3% vs 12.0%+/-19.6% overweight; P=.004). The difference in obesity between children with asthma and controls was significant for both sexes and across the 4.5 to 10.9 years and 11 to 16 years age groups. Asthma severity was not related to obesity.
Asthma is a risk factor for obesity in children and adolescents.
探讨儿童及青少年哮喘与肥胖之间的关系。
病历回顾。
城市社区卫生中心。
171名4至16岁儿童，其中85名患有哮喘，86名作为非哮喘对照。
哮喘诊断、年龄及按年龄和性别调整的体重指数（体重千克数除以身高米数的平方）。
样本中78%为西班牙裔，17%为非裔美国人，2%为白人，3%为其他少数族裔。与对照组（11.6%）相比，哮喘患儿中非常肥胖（体重指数≥第95百分位数）的比例显著更高（30.6%）（P = 0.004）。哮喘患儿超重的比例也显著高于对照组（均值±标准差，超重比例为22.5%±28.3% 对12.0%±19.6%；P = 0.004）。哮喘患儿与对照组在肥胖方面的差异在男女两性以及4.5至10.9岁和11至16岁年龄组中均有显著性。哮喘严重程度与肥胖无关。
哮喘是儿童及青少年肥胖的一个危险因素。
