Osborne J E, Bourke J F, Holder J, Colloby P, Graham-Brown R A
Department of Dermatology, Leicester Royal Infirmary, U.K.
Br J Dermatol. 1998 Mar;138(3):418-21. doi: 10.1046/j.1365-2133.1998.02117.x.
The value of pigmented lesion clinics (PLCs) for the early detection and treatment of malignant melanoma has been questioned. We have examined the effect of the introduction of a PLC on the referral interval between patients with melanoma presenting to their general practitioner (GP) and their attendance at hospital. The case notes of all patients presenting with melanoma in Leicestershire between 1984 and 1994 were reviewed. There was a significant initial reduction in the mean referral interval following the introduction of the PLC from 27.9 days (SEM = 6.6) in 1984 to 11.3 (2.3) days in 1987 (P < 0.01). However, the referral interval gradually rose over the following 7 years to a mean of 20.4 (4.4) days in 1994, which was not significantly better than the 1985/86 level. The increase in the referral interval was due to a greater percentage of melanomas being referred to clinics other than the PLC. Only 48% of melanomas were referred to the PLC in 1994 compared with 70% in 1987. We also reviewed the referral letters for those patients presenting in 1991 and 1994, and decided, on the basis of the content of the letter, whether the GP had suspected the diagnosis of melanoma. More than 50% of the melanomas were correctly diagnosed by the GP, but only half of these were then appropriately referred to the PLC. We believe that PLCs are of value in the early diagnosis and treatment of melanoma, but only if they are appropriately utilized by GPs.
色素沉着病变诊所(PLCs)在恶性黑色素瘤早期检测和治疗方面的价值受到了质疑。我们研究了引入PLC对黑色素瘤患者从向其全科医生(GP)转诊到入院就诊间隔时间的影响。回顾了1984年至1994年间在莱斯特郡出现黑色素瘤的所有患者的病历。引入PLC后,平均转诊间隔时间最初有显著缩短,从1984年的27.9天(标准误=6.6)降至1987年的11.3天(2.3)(P<0.01)。然而,在接下来的7年里,转诊间隔时间逐渐上升,到1994年平均为20.4天(4.4),并不比1985/86年的水平显著更好。转诊间隔时间的增加是由于转诊到PLC以外诊所的黑色素瘤患者比例更高。1994年只有48%的黑色素瘤患者被转诊到PLC,而1987年为70%。我们还查阅了1991年和1994年就诊患者的转诊信,并根据信件内容判断全科医生是否怀疑黑色素瘤的诊断。超过50%的黑色素瘤被全科医生正确诊断,但其中只有一半随后被适当地转诊到PLC。我们认为,PLCs在黑色素瘤的早期诊断和治疗中具有价值,但前提是全科医生要合理利用它们。