犬类尿石症。IV：结石的品种、矿物质成分、解剖位置及尿路感染情况之间的相互关系调查。

Urolithiasis in dogs. IV: Survey of interrelations among breed, mineral composition, and anatomic location of calculi, and presence of urinary tract infection.

作者信息

Ling G V, Franti C E, Johnson D L, Ruby A L

机构信息

Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis 95616, USA.

出版信息

Am J Vet Res. 1998 May;59(5):650-60.

PMID:9582971

Abstract

OBJECTIVE

To compile and analyze selected data from a large number of canine urinary calculus specimens that were subjected to quantitative, layer-by-layer mineral analysis.

SAMPLE POPULATION

11,000 canine urinary calculus specimens: 5,781 from female dogs, 5,215 from male dogs, and 4 from dogs of unrecorded sex.

PROCEDURE

Records of the Urinary Stone Analysis Laboratory, School of Veterinary Medicine, University of California were used to compile information regarding urinary calculus specimens from dogs. Records surveyed were of all canine calculi submitted for analysis between July 1981 and January 1994. Results analyzed included those of a mixed-breed group and 26 common breeds of stone-forming dogs. Interrelations of breed, sex, and age of the affected dogs, mineral composition of the specimens, and associated urinary tract infections were analyzed statistically.

RESULTS

Proportions of culture-positive specimens were significantly correlated between the sexes (r = 0.494, P = 0.008). Staphylococcus intermedius was isolated most often from either sex, ranging from 36.1% (Basset Hounds) to 67.9% (Pekingese) of cultured specimens from females and 8.7% (Chihuahuas) to 71.4% (Scottish Terriers) of specimens from males. The second most frequently isolated bacterial species, Escherichia coli, ranged from 0% in males of 2 breeds and females of 4 breeds to 25% in Cairn Terrier males and 19.4% in Basset Hound females. Streptococcus spp were the third most frequently isolated bacterial species. Significant correlations between the sexes were found for percentages of calculi located in the urinary bladder (r = 0.490, P = 0.008), and for calculi voided in the urine (r = 0.503, P = 0.006).

CONCLUSIONS

Breed and sex differences in prevalence of urolithiasis- and mineral-associated bacterial infections are numerous. Staphylococcus intermedius was the most common isolate from specimens from all but 3 of 54 breed/sex groupings. For either sex, streptococcal infections were significantly related to proportions of calculi passed in the urine.

摘要

目的

对大量经逐层次定量矿物分析的犬类尿结石标本的选定数据进行汇编和分析。

样本群体

11,000份犬类尿结石标本：5,781份来自雌性犬，5,215份来自雄性犬，4份来自未记录性别的犬。

方法

利用加利福尼亚大学兽医学院尿石分析实验室的记录，汇编有关犬类尿结石标本的信息。所调查的记录为1981年7月至1994年1月间提交分析的所有犬类结石。分析的结果包括一个混种犬组以及26种常见结石形成犬种的结果。对患病犬的品种、性别和年龄、标本的矿物质组成以及相关的尿路感染之间的相互关系进行了统计学分析。

结果

培养阳性标本的比例在两性之间存在显著相关性（r = 0.494，P = 0.008）。中间葡萄球菌在两性中分离率最高，在雌性培养标本中占36.1%（巴吉度猎犬）至67.9%（北京犬），在雄性标本中占8.7%（吉娃娃犬）至71.4%（苏格兰梗犬）。第二常见的分离细菌种类大肠杆菌，在2个品种的雄性和4个品种的雌性中为0%，在凯恩梗雄性中为25%，在巴吉度猎犬雌性中为19.4%。链球菌属是第三常见的分离细菌种类。在位于膀胱的结石百分比（r = 0.490，P = 0.008）以及随尿液排出的结石（r = 0.503，P = 0.006）方面，两性之间存在显著相关性。