λ阻遏蛋白调控PR启动子和Prm启动子之间的转换。
Lambda repressor regulates the switch between PR and Prm promoters.
作者信息
Walz A, Pirrotta V, Ineichen K
出版信息
Nature. 1976 Aug 19;262(5570):665-9. doi: 10.1038/262665a0.
DOI:10.1038/262665a0
PMID:958438
Abstract
The DNA region containing the Or operator, Pr and Prm promoters and their transcription initiations is sequenced. By binding to Or, repressor turns off Pr, turns on Prm and at higher concentrations turns off Prm, regulating its own synthesis. Prm mRNA is unique in beginning immediately with the initiation of translation, without a preceding leader sequence.
摘要
对包含Or操纵子、Pr和Prm启动子及其转录起始位点的DNA区域进行测序。通过与Or结合，阻遏蛋白关闭Pr，开启Prm，并在较高浓度时关闭Prm，从而调节其自身的合成。Prm mRNA的独特之处在于其翻译起始时没有前导序列，直接从起始密码子开始。
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