Egeland G M, Perham-Hester K A, Gessner B D, Ingle D, Berner J E, Middaugh J P
National Center for Environmental Health, Centers for Disease Control and Prevention, AK, USA.
Am J Public Health. 1998 May;88(5):781-6. doi: 10.2105/ajph.88.5.781.
The prevalence and characteristics of fetal alcohol syndrome cases and the usefulness of various data sources in surveillance were examined in Alaska to guide prevention and future surveillance efforts.
Sixteen data sources in Alaska were used to identify children with fetal alcohol syndrome. Medical charts were reviewed to verify cases, and records were reviewed to provide descriptive data.
Fetal alcohol syndrome rates varied markedly by birth year and race, with the highest prevalence (4.1 per 1000 live births) found among Alaska Natives born between 1985 and 1988. Screening and referral programs to diagnostic clinics identified 70% of all recorded cases. The intervention program for children 0 to 3 years of age detected 29% of age-appropriate cases, and Medicaid data identified 11% of all cases; birth certificates detected only 9% of the age-appropriate cases.
Our findings indicate a high prevalence of fetal alcohol syndrome in Alaska and illustrate that reliance on any one data source would lead to underestimates of the extent of fetal alcohol syndrome in a population.
在阿拉斯加对胎儿酒精综合征病例的患病率及特征，以及监测中各种数据来源的效用进行了研究，以指导预防工作和未来的监测工作。
利用阿拉斯加的16个数据来源来识别患有胎儿酒精综合征的儿童。查阅病历以核实病例，并审查记录以提供描述性数据。
胎儿酒精综合征的发病率因出生年份和种族而有显著差异，1985年至1988年出生的阿拉斯加原住民中患病率最高（每1000例活产中有4.1例）。诊断诊所的筛查和转诊项目识别出了所有记录病例的70%。针对0至3岁儿童的干预项目检测出了29%适合该年龄段的病例，医疗补助数据识别出了所有病例的11%；出生证明仅检测出了9%适合该年龄段的病例。
我们的研究结果表明阿拉斯加胎儿酒精综合征的患病率很高，并表明仅依赖任何一个数据来源都会导致对人群中胎儿酒精综合征程度的低估。
