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[我们用于研究重症肌无力患者肌肉疲劳性的肌动描记器改良版]

[Our modification of ergograph for studying muscle fatigability in myasthenia].

作者信息

Orzeł S, Lukasiewicz M, Rzepecki W

出版信息

Neurol Neurochir Pol. 1976 Jul-Aug;10(4):479-84.

PMID:958575
Abstract

The authors designed and made an ergograph of own modification and elaborated normal values of fatiguability half-time on the basis of 51 healthy subjects comparing the results with those in a group of 41 myasthenics subjected to thymectomy. The fatiguability half-time was determined in groups of muscles in the hand, axilla and popliteal area and masseters before and 14 days after thymectomy. The ergographic record was obtained without application of drugs as well as at the peak of activity of drugs and at the peak of activity of those after 5 mg Tensilon dose. The investigation made it possible to determine the muscle power before and after tymectomy. The Tensioln test at the peak activity of drugs permitted to establish the necessary dose of anticholinesterase drugs, especially after the operation.

摘要

作者设计并制作了一种自行改良的肌力描记器,并基于51名健康受试者制定了疲劳半衰期的正常值,同时将结果与41名接受胸腺切除术的重症肌无力患者组进行比较。在胸腺切除术前和术后14天,对手部、腋窝、腘窝区域的肌群以及咬肌的疲劳半衰期进行测定。肌力描记记录是在未使用药物时、药物活性峰值时以及注射5毫克腾喜龙后药物活性峰值时获取的。该研究能够确定胸腺切除术前和术后的肌肉力量。在药物活性峰值时进行腾喜龙试验有助于确定抗胆碱酯酶药物的必要剂量,尤其是在术后。

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