Mechanistic investigation of photoreduction of 5-bromouracil-containing oligomers.
作者信息
Fujimoto K, Ishihara S, Saito I
机构信息
Department of Synthetic Chemistry and Biological Chemistry, Faculty of Engineering, Kyoto University, Japan.
出版信息
Nucleic Acids Symp Ser. 1997(37):89-90.
PMID:9586013
Abstract
It was found that photoreduction of 5-bromouracil (BrU) occurs at 5'-ATBrU-3' sequence more efficiently than 5'-ABrU-3'. We introduced 5'-GG-3' sequence at the 5'-side of 5'-ATBrU-3' sequence and 5'-ABrU-3' sequence and investigated their photoreduction. As a result, dIz, an oxidation product originated from guanine cation radical, was detected.
摘要
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