Bauer M W, Driskill L E, Kelly R M
Department of Chemical Engineering, North Carolina State University, Raleigh 27695-7905, USA.
Curr Opin Biotechnol. 1998 Apr;9(2):141-5. doi: 10.1016/s0958-1669(98)80106-7.
Glycosyl hydrolases from hyperthermophiles are, thus far, the most widely studied enzyme class from these organisms. Not only are there many biotechnological opportunities for these enzymes, but the rapidly increasing amount of information about their genetic, biochemical and biophysical characteristics (recently genomic sequencing data for both P. furiosus and P. horikoshi have been published on the Internet) make them ideal candidates for the study of biocatalysis and protein thermostability at extremely high temperatures.