Novak S J
City of Hope National Medical Center/Beckman Research Institute, Duarte, CA, USA.
Endeavour. 1998;22(1):21-3. doi: 10.1016/s0160-9327(98)01096-5.
Psychedelic drugs are making a comeback. Proponents of psychedelics point to the widespread medical experimentation with mescaline and lysergic acid diethylamide-125 (LSD) in the 1950s as proof of their safety and efficacy. However, a review of the private and published writings of Sidney Cohen, MD, who conducted the first study of the safety of psychedelics, reveals that serious medical concerns about psychedelics arose before the public backlash against the drugs in the 1960s. The story of psychedelic research is a reminder of the inevitable complications involved in testing drugs on human subjects.
迷幻药物正在卷土重来。迷幻药物的支持者指出,20世纪50年代对三甲氧苯乙胺和麦角酸二乙酰胺-125(LSD)进行的广泛医学试验证明了它们的安全性和有效性。然而,对西德尼·科恩医生(MD)的私人及已发表著作进行的回顾显示,在20世纪60年代公众对这些药物产生强烈反对之前,就已经出现了对迷幻药物的严重医学担忧。西德尼·科恩医生进行了第一项关于迷幻药物安全性的研究。迷幻药物研究的故事提醒人们,在人体上进行药物测试不可避免地会出现各种复杂问题。