Radford D R, Challacombe S J, Walter J D
Department of Prosthetic Dentistry, United Medical and Dental Schools, Guys Dental Hospital, University of London, United Kingdom.
Int J Prosthodont. 1998 Jan-Feb;11(1):75-81.
The purpose of this study was to investigate in vitro the levels of adhesion of phenotypically switched and nonswitched Candida albicans to the smooth and rough surfaces of heat-cured acrylic resin, Molloplast B, and Novus.
Nonswitched and switched cells of C. albicans 3153A were prepared and adhesion assays were performed.
There was no difference in the level of adhesion of blastospores in their nonswitched or switched state. The adherence of hyphae to all three denture base materials was statistically significantly increased when in a switched form. There was greater adhesion to the two soft lining materials than to the acrylic resin.
Rough surfaces promote adhesion. There was no significant difference in the adhesion of switched and nonswitched blastospores, but there was increased adhesion of hyphal cells.
本研究的目的是在体外研究表型转换和未转换的白色念珠菌对热固化丙烯酸树脂、Molloplast B和Novus的光滑及粗糙表面的黏附水平。
制备白色念珠菌3153A的未转换和转换细胞，并进行黏附试验。
芽生孢子在未转换或转换状态下的黏附水平没有差异。菌丝以转换形式存在时，对所有三种义齿基托材料的黏附在统计学上显著增加。与丙烯酸树脂相比，对两种软衬材料的黏附性更强。
粗糙表面促进黏附。转换和未转换的芽生孢子的黏附没有显著差异，但菌丝细胞的黏附增加。
