Lester R S, Knowles S R, Shear N H
Division of Dermatology, Sunnybrook Health Science Centre, University of Toronto, Ontario, Canada.
Dermatol Clin. 1998 Apr;16(2):277-88. doi: 10.1016/s0733-8635(05)70010-3.
Because of their potent antiinflammatory and immunosuppressive properties, systemic corticosteroids are used to modify a vast array of diseases. This class of drugs, however, has the potential to produce multiple adverse effects presenting the dermatologist with difficult decisions in the management of patients with potentially steroid responsive disorders. This article reviews the side effects of systemic corticosteroids, comments on strategies to minimize these side effects, as well as, outlining suggested mechanisms by which physicians may minimize the risks of medical legal consequences owing to adverse reactions to these drugs.
由于其强大的抗炎和免疫抑制特性，全身性皮质类固醇被用于治疗多种疾病。然而，这类药物有可能产生多种不良反应，这给皮肤科医生在管理可能对类固醇有反应的疾病患者时带来了艰难的决策。本文回顾了全身性皮质类固醇的副作用，评论了将这些副作用降至最低的策略，并概述了医生可通过哪些建议机制将因这些药物不良反应导致的医疗法律后果风险降至最低。
