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尼日利亚洁牙棒提取物对牙周病原菌的体外抗菌作用

In-vitro antibacterial effects of extracts of Nigerian tooth-cleaning sticks on periodontopathic bacteria.

作者信息

Sote E O, Wilson M

机构信息

Department of Children's Dentistry, Eastman Dental Institute, London.

出版信息

Afr Dent J. 1995;9:15-9.

PMID:9590895
Abstract

Aqueous extracts from 8 plants used for tooth-cleaning in Nigeria were tested for their ability to inhibit the growth of five periodontopathic bacteria, Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, Eikenella corrodens and Campylobacter rectus. Extracts of all the plants except that of Massularia acuminata exhibited varying growth inhibitory potentials on the microorganisms. Extract of Terminalia glaucescens showed the widest spectrum of activity, inhibiting the growth of all the tested bacteria except P. gingivalis. These findings corroborate other studies that the plants possess antiplaque properties and suggest that they may be useful tools in preventive dentistry in poor developing countries. However, the bioavailability of the active ingredients of the plants and their long term effects in vivo need to be investigated.

摘要

对尼日利亚用于清洁牙齿的8种植物的水提取物进行了测试,以检验其抑制5种牙周病原菌生长的能力,这5种病原菌分别是牙龈卟啉单胞菌、中间普氏菌、具核梭杆菌、腐蚀艾肯菌和直肠弯曲菌。除尖叶马苏铁外,所有植物的提取物对这些微生物均表现出不同程度的生长抑制潜力。灰绿诃子提取物的活性谱最广,除牙龈卟啉单胞菌外,能抑制所有受试细菌的生长。这些发现证实了其他研究结果,即这些植物具有抗牙菌斑特性,并表明它们可能是贫困发展中国家预防牙科领域的有用工具。然而,这些植物活性成分的生物利用度及其在体内的长期影响仍有待研究。

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